Publications by authors named "Dijia Zhou"
Article Synopsis
- Human brucellosis is a significant public health issue in Shaanxi Province, China, and understanding its transmission patterns is essential for creating effective control strategies.
- The study identified 189 strains of the pathogen using bio-typing and whole genome sequencing, revealing genetic diversity with two clades (A and B) and 19 sequence types (STs).
- The findings indicate that the outbreak is fueled by multiple indigenous lineages, highlighting the need for targeted control measures to address this zoonotic disease.
The Multiple Roles of XBP1 in Regulation of Glucose and Lipid Metabolism.
Curr Protein Pept Sci
March 2018
X-box binding protein1 (XBP1) especially exerts its fundamental effects in the cellular organelle endoplasmic reticulum (ER) via affecting three trans-membrane stress sensor proteins: PKRlike ER kinase (PERK), inositol-requiring enzyme 1(IRE1) and activating transcription factor 6(ATF6). At the center of XBP1's broad effects is its remarkable metabolic housekeeper function. XBP1 decreased glucose dysfunction via funneling its effects on improving insulin sensitivity and stimulating insulin secretion.
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