Publications by authors named "Difei Lian"
IgG4-related disease (IgG4-RD) is a chronic multi-organ immune fibroinflammatory disorder. It can affect almost any organ, with the primary treatment being corticosteroids, sometimes supplemented with conventional immunosuppressants or biological agents, such as rituximab therapy. The occurrence of this disease is associated with aberrant adaptive immune responses, but its specific pathological mechanisms remain unclear.
View Article and Find Full Text PDFPneumatosis cystoides intestinalis in granulomatosis with polyangiitis: a case report.
Clin Rheumatol
December 2024
Article Synopsis
- This study explores the rare condition of pneumatosis cystoides intestinalis (PCI) in a patient with granulomatosis with polyangiitis (GPA), highlighting its clinical and imaging features.
- The case involves a 71-year-old woman with GPA who showed no symptoms of PCI despite CT scans indicating gas in her colon wall, stressing the need for careful monitoring in similar patients.
- The findings suggest that PCI can occur in GPA patients without typical symptoms, pointing to a need for further investigation into the mechanisms and treatment of this unusual complication.
Background: To systematically describe clinical characteristics and investigate factors associated with COVID-19-related infection, hospital admission, and IgG4-related disease relapse in IgG4-RD patients.
Methods: Physician-reported IgG4-RD patients were included in this retrospective study. Using multivariable logistic regression analysis to determine factors for primary outcome (COVID-19-related IgG4-RD relapse) and secondary outcome (COVID-19-related infection and hospital admission).
Osteoporosis (OP) is a systemic bone disease in which bone density and quality decrease and bone fragility increases due to a variety of causes, making it prone to fractures. The development of OP is closely related to oxidative stress. Uric acid (UA) is the end product of purine metabolism in the human body.
View Article and Find Full Text PDFSGLT-2 Inhibitors for Non-Alcoholic Fatty Liver Disease: A Review.
Front Biosci (Landmark Ed)
July 2023
Non-alcoholic fatty liver disease (NAFLD) is a group of metabolic liver illnesses that lead to accumulation of liver fat mainly due to excessive nutrition. It is closely related to insulin resistance, obesity, type 2 diabetes, and cardiovascular disease, and has become one of the main causes of chronic liver disease worldwide. At present, there is no specific drug for the treatment of NAFLD; lifestyle interventions including dietary control and exercise are recommended as routine treatments.
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