Publications by authors named "Dieter O Mayer"
Wound Bed Preparation 2021.
Adv Skin Wound Care
April 2021
General Purpose: To present the 2021 update of the Wound Bed Preparation paradigm.
Target Audience: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.
Learning Objectives/outcomes: After participating in this educational activity, the participant will: 1.
Article Synopsis
- - Products that create a protective skin barrier are essential for shielding the skin from damaging bodily fluids like sweat and wound exudate.
- - Various barrier products, including those with petrolatum, zinc oxide, silicone polymers, and cyanoacrylates, are clinically effective, but film-forming polymers and cyanoacrylates are noted for being easier to apply and more affordable.
- - Research shows that concentrated cyanoacrylate offers superior protection against moisture and abrasion, while silicone creams with micronutrients effectively reduce pressure ulcer risk when used in prevention strategies.
Article Synopsis
- Chronic wounds often display prolonged inflammation, leading to symptoms like increased devitalised tissue, exudate, pain, and malodour, which can negatively impact a patient's quality of life.
- The presence of necrotic tissue can promote bacterial growth and infection, causing further complications such as pain and limited mobility.
- Concentrated surfactant-based gels like Plurogel can aid in wound cleansing and management, showing promising results in clinical case studies by reducing inflammation and improving overall well-being when used with standard care.
A biofilm is a community of microorganisms that adhere to each other and to surfaces and secrete extracellular polymeric substances (EPS) encasing themselves in a matrix. Biofilms are a major healthcare concern, as they can form on medical devices leading to infection. Additionally, there is growing evidence to show their ability to form in chronic wounds, which leads to delayed wound healing and inflammation.
View Article and Find Full Text PDFBackground: Controlled limb reperfusion has been shown to prevent the deleterious effects of ischemia-reperfusion (IR) syndrome following revascularization of acute limb ischemia (ALI). To reduce the production of cell-toxic oxygen-free radicals, we have established a new initially oxygen-free, hypothermic, heparin-coated perfusion and hemofiltration system and report on our first results.
Methods: In a retrospective single-center study, controlled limb reperfusion was applied in 36 patients (64.
In wound care research, available high-level evidence according to the evidence pyramid is rare, and is threatened by a poor study design and reporting. Without comprehensive and transparent reporting, readers will not be able to assess the strengths and limitations of the research performed. Randomized clinical trials (RCTs) are universally acknowledged as the study design of choice for comparing treatment effects.
View Article and Find Full Text PDFBackground: Femoro-femoral veno-arterial perfusion is an established circulatory support and cooling method for thoracic- and/or thoracoabdominal aortic aneurysm repair. However, retrograde perfusion through femoral arteries can lead to retrograde cerebral embolization and neurologic dysfunction after surgery. To avoid these complications, we have established a femoro-femoral veno-venous perfusion technique and evaluated its safety and effectiveness in elective and nonelective patients.
View Article and Find Full Text PDFBackground: Approximately 20% of leg ulcers remain unresponsive to the best conservative standard of care. So far, these patients could either receive conventional skin grafts or had to accept their intractable wound. Skin substitutes from cell culture may represent a promising alternative to heal a major part of these patients on a non-surgical, potentially more cost-effective basis.
View Article and Find Full Text PDF