[Burden and Rehabilitation Goals of Families in Pediatric-oncological Rehabilitation].

Burden and Rehabilitation Goals of Families in Pediatric-oncological Rehabilitation Survival rates of childhood cancer patients increased during the past years up to 80 %. Therefore, pediatric oncological rehabilitation is essential for reintegrating children with cancer into normal life. We performed an analysis of the current state in pediatric oncological rehabilitation with regards to the impairments of the participants and results in rehabilitation.

[Burden of Parents of Pediatric Cancer Patients in Pediatric-oncological Rehabilitation].

Burden of Parents of Pediatric Cancer Patients in Pediatric-oncological Rehabilitation All family members experience high burden in case of paediatric cancer. Family-oriented rehabilitation (FOR) aims to improve the physical and mental situation of the families. We investigated anxiety and depression (HADS) and cancer-related burden of parents (n = 69) before and after FOR and analysed its association with quality of life of the ill children.

Evidence-Based Hernia Treatment in Adults.

Background: Inguinal hernia repair is the most common general surgical procedure in industrialized countries, with a frequency of about 200 operations per 100 000 persons per year. Suture- and mesh-based techniques can be used, and the procedure can be either open or minimally invasive.

Methods: This review is based on a selective search of the literature, with interpretation of the published findings according to the principles of evidence-based medicine.

What is a Certified Hernia Center? The Example of the German Hernia Society and German Society of General and Visceral Surgery.

To date, the scientific definition "hernia center" does not exist and this term is being used by hospitals and private institutions as a marketing instrument. Hernia surgery has become increasingly more complex over the past 25 years. Differentiated use of the various techniques in hernia surgery has been adopted as a "tailored approach" program and requires intensive engagement with, and extensive experience of, the entire field of hernia surgery.

Peritoneal resorption capacity for the inflammatory mediators in acute experimental Staphylococcus aureus peritonitis.

Background: Elevations in both endotoxin and interleukin-6 (IL-6) concentrations in peritoneal exudates are a thousand times higher than their respective concentrations in the peripheral blood in patients with gram-positive or gram-negative peritonitis. We aimed in this study to evaluate the resorption capacity of the peritoneum for endotoxin and IL-6 in a model of bacterial (gram-positive) peritonitis.

Methods: Intraperitoneal (i.

[Course of psychosocial distress and health-related quality of life in patients at different age groups during cancer rehabilitation].

Objectives: This study investigates psychosocial distress and health-related quality of life in younger (up to 40 years), middle-aged (up to 50 years), and elderly cancer patients (up to 60 years).

Methods: 637 patients (94%women, 75% breast-cancer patients) completed validated questionnaires measuring distress, anxiety, depression, fear of progression, and quality of life at the beginning (T0) and the end (T1) of a cancer rehabilitation program (T0/T1 response rate: 72 %) as well as at 1-year follow-up (T2) (n = 485, T2 response rate: 76 %).

Results: Patients in the different age groups did not differ significantly in psychosocial distress at T0 except for fear of progression, which is lower among the younger age group.

Endotoxemia and endotoxin tolerance in patients with ARDS.

Background: The significance of endotoxemia in man is controversial, induces cytokine release and stimulates the immune system. Exaggerated cytokine release of mononuclear cells was observed in acute lung injury/acute respiratory distress syndrome (ALI/ARDS). However, repetitive administration of endotoxin can cause tolerance.

Laparoscopic repair of parastomal hernias: a single surgeon's experience in 66 patients.

Introduction: The repair of parastomal hernias represents a surgical problem with high complication and failure rates. A basic principle is the necessity of mesh-based techniques. The study was performed to evaluate a laparoscopic approach, primarily based on the intraperitoneal on lay mesh technique.

Preoperative immunonutrition suppresses perioperative inflammatory response in patients with major abdominal surgery-a randomized controlled pilot study.

Background/aim: Perioperative administration of immunoenriched diets attenuates the perioperative inflammatory response and reduces postoperative infection complications. However, many questions still remain unresolved in this area, such as the length of diet administration, diet composition, and the mechanisms involved. We performed an open, randomized, triple-arm study comparing the effect of two perioperative feeding regimens with a postoperative one.

Photosynthetic performance of an Arabidopsis mutant with elevated stomatal density (sdd1-1) under different light regimes.

In the Arabidopsis mutant sdd1-1, a point mutation in a single gene (SDD1) causes specific alterations in stomatal density and distribution. In comparison to the wild type (C24), abaxial surfaces of sdd1-1 rosette leaves have about 2.5-fold higher stomatal densities.

Small intestinal bacterial overgrowth in human cirrhosis is associated with systemic endotoxemia.

Objectives: Systemic endotoxemia has been implicated in various pathophysiological sequelae of chronic liver disease. One of its potential causes is increased intestinal absorption of endotoxin. We therefore examined the association of small intestinal bacterial overgrowth with systemic endotoxemia in patients with cirrhosis.

The subtilisin-like serine protease SDD1 mediates cell-to-cell signaling during Arabidopsis stomatal development.

Wild-type stomata are distributed nonrandomly, and their density is controlled by endogenous and exogenous factors. In the Arabidopsis mutant stomatal density and distribution1-1 (sdd1-1), the establishment of the stomatal pattern is disrupted, resulting in stomata clustering and twofold to fourfold increases in stomatal density. The SDD1 gene that encodes a subtilisin-like Ser protease is expressed strongly in stomatal precursor cells (meristemoids and guard mother cells), and the SDD1 promoter is controlled negatively by a feedback mechanism.