Open Innovation or Traditional Patenting Strategies to Efficiently Address Health Emergencies? How Patent Information Was Used Towards Effective Treatments for COVID-19.

Introduction/objective: During the 1150 days of COVID-19 pandemic there were great efforts to develop efficient treatments for the disease. After this long time, some drugs emerged as treatment for COVID-19. Some of them are new drugs, most of them, known drugs.

Information Disclosed in Patent Documents being the Source to Address Emergencies: A Strategy to Achieve Technological Developments Addressing COVID-19.

Background: Face COVID-19 pandemic, a need for accurate information on SARS-CoV-2 virus is urgent and scientific reports have been published on a daily basis to enable effective technologies to fight the disease progression. However, at the initial occurrence of Pandemic, no information on the matter was known and technologies to fight the Pandemic were not readily available. However, searches in patent databases, if strategically designed, can offer quick responses to new pandemics.

Phe-Phe Di-Peptide Nanostructure Self-Assembling Modulated by Luminescent Additives.

In this work, supramolecular l-l-diphenylalanine (Phe-Phe) nanostructures were self-assembled in solvents of distinct polarity and in the presence of luminescent additives of distinct conjugation length that physically adhere to the nanostructures to provide growth environments of distinct properties. When the additive is poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene], an electron donor polymer, and solvent is tetrahydrofuran (THF), Phe-Phe vesicle-like structures are obtained, whereas in water and in the presence of a similar additive in structure, poly[5-methoxy-2-(3-sulfopropoxy)-1,4-phenylenevinylene], nanotubes are formed. In contrast, when 9-vinyl-carbazole, an electron acceptor additive is used, nanotubes are formed even when THF is the solvent.