The overlooked role of excited anion states in NiO2- photodetachment.

Photodetachment spectra of anionic species provide significant insights into the energies and nature of ground and excited states of both the anion and resultant neutral molecules. Direct detachment of the excess electron to the continuum may occur via formally allowed or forbidden transitions (perhaps as the result of intensity borrowing through vibronic coupling). However, alternate indirect pathways are also possible and often overlooked.

Bacterial risk factors for treatment failure and relapse among patients with isoniazid resistant tuberculosis.

Background: Drug resistant tuberculosis (TB) is increasing in prevalence worldwide. Treatment failure and relapse is known to be high for patients with isoniazid resistant TB treated with standard first line regimens. However, risk factors for unfavourable outcomes and the optimal treatment regimen for isoniazid resistant TB are unknown.

Same but Different: Dipole-Stabilized Shape Resonances in CuF(-) and AgF(.).

Electron attachment to closed-shell molecules is a gateway to various important processes in the gas and condensed phases. The properties of an electron-attached state, such as its energy and lifetime as well as the character of the molecular orbital to which the electron is attached, determine the fate of the anion. In this experimental and theoretical study of copper and silver fluoride anions, we introduce a new type of metastable anionic state.

The effect of the dipole bound state on AgF⁻ vibrationally resolved photodetachment cross sections and photoelectron angular distributions.

The first photoelectron spectra of AgF(-) are recorded over the energy range 1.61-1.85 eV using the velocity map imaging technique.

Photoelectron angular distributions as probes of cluster anion structure: I(-)·(H2O)2 and I(-)·(CH3CN)2.

The use of photoelectron angular distributions to provide structural details of cluster environments is investigated. Photoelectron spectra and angular distributions of I(-)·(H2O)2 and I(-)·(CH3CN)2 cluster anions are recorded over a range of photon energies. The anisotropy parameter (β) for electrons undergoes a sharp change (Δβmax) at photon energies close to a detachment channel threshold.

Photodetachment and photodissociation of the linear OCuO- molecular anion: energy and time dependence of Cu- production.

A photodissociative study of CuO2(-) is presented using a combination of energy and time domain photoelectron spectroscopy. Ion source conditions are used that solely produce linear OCuO(-). Photodissociation of this isomer to produce Cu(-) + O2 is conclusively demonstrated at wavelengths between 765 and 340 nm.

Inter-channel effects in monosolvated atomic iodide cluster anion detachment: correlation of the anisotropy parameter with solvent dipole moment.

Photoelectron imaging results are presented for I(-)[middle dot]X cluster anions (X = CO(2), C(4)H(5)N [pyrrole], (CH(3))(2)CO, CH(3)NO(2)). The available detachment channels are labeled according to the neutral iodine atom states produced (channel I ≡ (2)P(3/2) and channel II ≡ (2)P(1/2)). At photon energies in the vicinity of the channel II threshold these data are compared to previously reported results for I(-)[middle dot]X (X = CH(3)CN, CH(3)Cl, CH(3)Br, and H(2)O).

Near threshold Cl(-)·CH3I photodetachment: apparent 2P1/2 channel suppression and enhanced 2P3/2 channel vibrational excitation.

Cl(-)·CH(3)I cluster anion photoelectron images are recorded over a range of detachment wavelengths in the immediate post threshold region. The photoelectron spectral features fall into two categories. A number of weak, photon energy dependent transitions are observed and attributed to atomic anion fragmentation products.

Rapid changes in shear stress induce dissociation of a G alpha(q/11)-platelet endothelial cell adhesion molecule-1 complex.

It has been recently shown that endothelial platelet endothelial cell adhesion molecule-1 (PECAM-1) expression is pro-atherogenic. PECAM-1 is involved in sensing rapid changes in fluid shear stress but the mechanisms for activating signalling complexes at the endothelial cell junction have yet to be elucidated. Additional studies suggest the activation of membrane-bound G proteins G alpha(q/11) also mediate flow-induced responses.

Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase.

Abuse of the dissociative anesthetic ketamine can lead to a syndrome indistinguishable from schizophrenia. In animals, repetitive exposure to this N-methyl-d-aspartate-receptor antagonist induces the dysfunction of a subset of cortical fast-spiking inhibitory interneurons, with loss of expression of parvalbumin and the gamma-aminobutyric acid-producing enzyme GAD67. We show here that exposure of mice to ketamine induced a persistent increase in brain superoxide due to activation in neurons of reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase.