Publications by authors named "Diego Tomassone"
Many factors may influence the risk of being infected by SARS-CoV-2, the coronavirus responsible for coronavirus disease 2019 (COVID-19). Exposure to the virus cannot explain the variety of an individual's responses to the virus and the high differences of effect that the virus may cause to some. While a person's preexisting condition and their immune defenses have been confirmed to play a major role in the disease progression, there is still much to learn about hosts' genetic makeup towards COVID-19 susceptibility and risk.
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- Life is fundamentally composed of atomic interactions, metabolism, and genetics, primarily involving elements like hydrogen, oxygen, and carbon, which together contribute to both normal cells and cancer cells.
- Understanding cancer's origins requires recognizing that cancer cells share structural and metabolic similarities with basic prokaryotic organisms, despite the persistent mysteries surrounding cancer despite extensive research.
- New scientific approaches highlight the role of electron behavior in cellular processes and emphasize the impact of magnetic fields on biological systems, suggesting that changes at atomic and metabolic levels in mitochondria could lead to the development of cancer cells.
Searching for a Link between Bone Decay and Diabetes Type 2.
Endocr Metab Immune Disord Drug Targets
September 2022
Article Synopsis
- The commentary discusses the potential connection between metabolic diseases like type 2 diabetes and bone degeneration.* -
- It highlights how these diseases may affect the differentiation of mesenchymal stem cells, which are crucial for bone development.* -
- Specifically, the focus is on the molecular mechanisms that prevent these stem cells from transforming into osteoblasts and osteocytes, important cells for maintaining healthy bones.*
The COVID-19 pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), still remains a severe threat. At the time of writing this paper, the second infectious wave has caused more than 280,000 deaths all over the world. Italy was one of the first countries involved, with more than 200,000 people reported as infected and 30,000 deaths.
View Article and Find Full Text PDFBackground: A novel coronavirus (SARS-CoV-2)-induced pneumonia (COVID-19) emerged in December 2019 in China, spreading worldwide. The aim of the present investigation was to evaluate the immunological response and the clinical subset of peripheral lymphocyte subset alteration in COVID-19 infection.
Methods: the study was conducted on four different clinical groups ( = 4; total = 138).
Background: Based on recent findings, we speculated the existence of the lung, heart, and kidney axis as the main pathway for the COVID-19 disease progression.
Methods: This paper reports on an observational study conducted by a team of researchers and doctors of the 118-Pre-Hospital and Emergency Department of SG Moscati of Taranto City in Italy. The study was conducted on a totality of 185 participants that were divided into three groups.
Sars-CoV-2 Virus Infection May Interfere CD34+ Hematopoietic Stem Cells and Megakaryocyte-Erythroid Progenitors Differentiation Contributing to Platelet Defection towards Insurgence of Thrombocytopenia and Thrombophilia.
Microorganisms
July 2021
To date, several cases of thrombosis have been confirmed to be related to Sars-CoV-2 infection. Multiple attempts detected the prolonged occurrence of Sars-CoV-2 viral RNA (long COVID) in whole blood suggesting that virus byproducts may remain within cells and tissues well over the disease has finished. Patients may develop severe thrombocytopenia, acute anemia of inflammation and, systemic thrombosis with the fatal course of disease, which is suggestive of further interferences of Sars-CoV-2 on hematopoietic stem cells (HSCs) within the differentiation process towards erythroid and megakaryocytic cells.
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