Percutaneous Surgery for Tailor's Bunion: A Comparative Study.

 To analyze and compare the clinical and radiographic outcomes of bunionette correction using two percutaneous surgical techniques: the Sponsel technique and the medial wedge osteotomy of the distal metaphysis. The results were evaluated individually and comparatively using the American Orthopaedic Foot and Ankle Society's Lesser Metatarsophalangeal-Interphalangeal Scale (AOFAS), Visual Analog Scale (VAS) for pain assessment, and radiographic measurements of the intermetatarsal angle IV-V (AIM4-5) and metatarsophalangeal angle of the fifth ray (AMF-5).  This was a retrospective study conducted from May 2011 to February 2022.

Expression patterns of Galectin-3 and NLRP3 in Chagas reactivation and graft damage in heart transplants.

Objective: This study aimed to assess the expression patterns of galectin-3 (Gal-3) and NLRP3 in heart transplant recipients according to the presence of reactivated Trypanosoma cruzi infection or allograft rejection in Chagas and non-Chagas heart transplant recipients.

Methods: Gal-3 and NLRP3 expression levels were analyzed in endomyocardial biopsies from 31 heart transplant recipients, including 16 patients with chronic Chagas disease (ChD) and 15 without ChD. Samples were evaluated during periods of graft rejection or ChD reactivation, characterized by intense myocardial cellular infiltrate, and after remission of the infiltrate, classified by histopathological severity.

A Reliable and Straightforward Combination of vortex-assisted Dispersive Magnetic solid-phase Extraction with Direct Sorbent Sampling for Highly Sensitive Silver Determination in Water Samples Using Flame and Metal Furnace AAS.

In the present paper, the assessment of vortex-assisted dispersive magnetic solid-phase extraction using amino-functionalized mesoporous combined with direct magnetic sorbent sampling (DMSS) in flame or furnace atomic absorption spectrometry (FAAS or FF-AAS) was demonstrated for highly sensitive silver determination in water samples. The developed method showed significant enrichment factors compared to conventional pneumatic nebulization by FAAS, 607 for DMSS-FF-AAS and 114 for DMSS-FAAS. The analytical curve showed linearity in the range from 5.

Atomic Structure and 3D Shape of a Multibranched Plasmonic Nanostar from a Single Spatially Resolved Electron Diffraction Map.

Despite the interest in improving the sensitivity of optical sensors using plasmonic nanoparticles (NPs) (rods, wires, and stars), the full structural characterization of complex shape nanostructures is challenging. Here, we derive from a single scanning transmission electron microscope diffraction map (4D-STEM) a detailed determination of both the 3D shape and atomic arrangement of an individual 6-branched AuAg nanostar (NS) with high-aspect-ratio legs. The NS core displays an icosahedral structure, and legs are decahedral rods attached along the 5-fold axes at the core apexes.

Sedentary behavior and self-harm in adolescents with asthma, rhinitis and eczema.

Objective: To investigate the association between allergic diseases and the tendency to self-harm in adolescents, considering the role of sedentary behavior.

Methods: This was a population-based cross-sectional study, carried out in 2022, with 727 adolescents aged 12 to 19 years, from a capital in the Northeast of Brazil. The authors evaluated the association between each allergic disease (asthma, rhinitis and eczema) and self-harm, sedentary behavior and other variables.

Impact of combined intermittent fasting and high-intensity interval training on apoptosis and atrophy signaling in rat fast- and slow-twitch muscles.

This study aimed to evaluate the influence of combined intermittent fasting (IF) and high-intensity interval training (HIIT) on morphology, caspase-independent apoptosis signaling pathway, and myostatin expression in soleus and gastrocnemius (white portion) muscles from healthy rats. Sixty-day-old male Wistar rats (n = 60) were divided into four groups: control (C), IF, high-intensity-interval training (T), and high-intensity-interval training and intermittent fasting (T-IF). The C and T groups received ad libitum chow daily; IF and T-IF received the same standard chow every other day.

Effect of modified citrus pectin on galectin-3 inhibition in cisplatin-induced cardiac and renal toxicity.

This study evaluated the effect of pharmacological inhibition of galectin 3 (Gal-3) with modified citrus pectin (MCP) on the heart and kidney in a model of cisplatin-induced acute toxicity. Male Wistar rats were divided into four groups (n = 6/group): SHAM, which received sterile saline intraperitoneally (i.p.

Changing trends in clinical characteristics and in-hospital mortality of patients with infective endocarditis over four decades.

Background: Infective endocarditis continues to be a significant concern and may be undergoing an epidemiological transition.

Methods: Were studied 1804 consecutive episodes of infective endocarditis between 1978 and 2022. The mean age was 48 ( ± 19), and 1162 (64%) patients were male.

[Screen time, quality of the adolescent diet, and profile of the school environment].

Adolescents from 30 state schools in Curitiba, State of Paraná, reported total screen time, namely television, video games and laptops. Diet quality was assessed by the frequency of food consumption. The income of the school environment was taken from the Census.

Nipple shield use in the maternity ward increases risk of exclusive breastfeeding interruption in the first six months of infant's life.

Objective: The objective of this study was to investigate the association between use of silicone nipple shields in the maternity ward and exclusive breastfeeding interruption in the first 6 months of the infant's life.

Design: Cohort study.

Setting: Interviews were conducted personally at the mother's home at 1 and 6 months postpartum and by telephone at 2 and 4 months.

The problem of conserving an ecosystem that has not been completely delineated and mapped: the case of the Cocais Palm Forest.

Land cover changes threaten biodiversity and alter the geographic distribution of forests worldwide. Studies on this topic are important to establish conservation strategies and public policies. However, different studies may propose different spatial representations due to differences when identifying, classifying, and/or mapping the same vegetation formation, as observed for the Cocais Forest region.

Bisphenol A disruption promotes mammary tumor microenvironment via phenotypic cell polarization and inflammatory response.

Inflammation in the established tumor microenvironment (TME) is often associated with a poor prognosis of breast cancer. Bisphenol A (BPA) is an endocrine-disrupting chemical that acts as inflammatory promoter and tumoral facilitator in mammary tissue. Previous studies demonstrated the onset of mammary carcinogenesis at aging when BPA exposure occurred in windows of development/susceptibility.

Unraveling surface-enhanced Raman spectroscopy results through chemometrics and machine learning: principles, progress, and trends.

Surface-enhanced Raman spectroscopy (SERS) has gained increasing attention because it provides rich chemical information and high sensitivity, being applicable in many scientific fields including medical diagnosis, forensic analysis, food control, and microbiology. Although SERS is often limited by the lack of selectivity in the analysis of samples with complex matrices, the use of multivariate statistics and mathematical tools has been demonstrated to be an efficient strategy to circumvent this issue. Importantly, since the rapid development of artificial intelligence has been promoting the implementation of a wide variety of advanced multivariate methods in SERS, a discussion about the extent of their synergy and possible standardization becomes necessary.

Pactolo Bar: An Approach to Mitigate the Midas Touch Problem in Non-Conventional Interaction.

New ways of interacting with computers is driving research, which is motivated mainly by the different types of user profiles. Referred to as non-conventional interactions, these are found with the use of hands, voice, head, mouth, and feet, etc. and these interactions occur in scenarios where the use of mouse and keyboard would be difficult.

Galectin-3 is a key hepatoprotective molecule against the deleterious effect of cisplatin.

Aims: Evaluate the role of galectin-3 in the liver using an acute model of cisplatin-induced toxicity.

Material And Methods: Modified citrus pectin (MCP) treatment was used to inhibit galectin-3. Rats were distributed into four groups: SHAM, CIS, MCP and MCP + CIS.

IMPACT OF COVID-19 ON MORTALITY AND HOSPITALIZATION IN OLDER ADULTS WITH HIP FRACTURE.

Objective: To evaluate the impact of the COVID-19 pandemic on hospital admission and mortality indicators in older adults with fractures of the proximal femur.

Methods: Observational and retrospective study that took place from June 2016 to 2020. Patients of both genders who underwent surgical treatment for fractures of the proximal end of the femur, aged over 60 years, were included.

Surface-enhanced Raman spectroscopy of one and a few molecules of acid 4-mercaptobenzoic in AgNP enabled by hot spots generated by hydrogen bonding.

The present study reports a direct approach to generate efficient hot spots using a nonresonant molecule bound to the inner part or hot spots that can increase the SERS sensitivity to obtain spectra of one and a few molecules. The 4-Mercaptobenzoic acid (4-MBA) adsorbate, connected to the Ag surface by a thiolate-Ag bonding, was able to trigger a self-assembly process of AgNP, which occurred by cooperative hydrogen bonds between the carboxylic groups of 4-MBA located in different nanoparticles when the pH was adjusted to 4. The self-assembly structure was characterized by UV-Vis spectroscopy and SERS (Surface Enhancement Raman Scattering), and DFT-based calculation of the model complex [AgNP-(4-MBA)-AgNP] was employed to improve the understanding of the self-assembled complex formation through the comparison of calculated and experimental SERS spectra.

New physics searches at kaon and hyperon factories.

Rare meson decays are among the most sensitive probes of both heavy and light new physics. Among them, new physics searches using kaons benefit from their small total decay widths and the availability of very large datasets. On the other hand, useful complementary information is provided by hyperon decay measurements.

Silica extraction from rice hull ash through the sol-gel process under ultrasound.

Rice is among the main foods produced in the world and is part of the daily diet of most families. The main waste from rice processing is rice husk (RH), which has been used as biomass for energy generation through combustion. In this process, rice husk ash (RHA) is generated as a residue, and its silica (SiO) content varies from 85 to 98%.

The role of annexin A1-derived peptide Ac on liver and kidney injuries induced by cisplatin in rats.

Aims: In this study we evaluated the effect of pharmacological treatment with AnxA1-derived peptide Ac in an experimental model of toxicity induced by cisplatin.

Main Methods: Male rats were divided into Sham (control), Cisplatin (received intraperitoneal injections of 10 mg/kg/day of cisplatin for 3 days) and Ac (received intraperitoneal injections of 1 mg/kg/day of peptide, 15 min before cisplatin) groups.

Key Findings: After 6 h of the last dose of cisplatin, an acute inflammatory response was observed characterized by a marked increase in the number of neutrophils and GM-CSF, IL-β, IL-6, IL-10 and TNF-α plasma levels.

Prostate Cancer Imaging: What We Already Know and What Is on the Horizon.

Conventional as well as advanced imaging modalities contribute to accurate detection of prostate cancer and have important roles in screening, staging, active surveillance, and evaluation for biochemical recurrence.

Simple and statistically sound recommendations for analysing physical theories.

Physical theories that depend on many parameters or are tested against data from many different experiments pose unique challenges to statistical inference. Many models in particle physics, astrophysics and cosmology fall into one or both of these categories. These issues are often sidestepped with statistically unsound ad hoc methods, involving intersection of parameter intervals estimated by multiple experiments, and random or grid sampling of model parameters.

Structural characterization and plasmonic properties of manganese oxide-coated gold nanorods.

The preparation of metal@(dielectric or semiconductor) core@shell hybrid materials have been shown promising for both SERS and SEF applications due to improved stability in the presence of ions and the adsorbate compared to non-covered metallic nanoparticles. However, fine control over the thickness of the covering layer is essential to maximize the intrinsic trade-off between the plasmonic enhancement and the chemical stability improvement. Here, the preparation of manganese dioxide ultrathin layers covered gold nanorods (AuNR@MnO) with varying thicknesses of the MnO layer is reported, and the characterization and evaluation of the resulting materials as SERS and SEF substrate.