Computational Analysis of the Influence of Menopause and Ageing on Bone Mineral Density, Exploring the Impact of Bone Turnover and Focal Bone Balance-A Study on Overload and Underload Scenarios.

This study aims to investigate the impact of hormonal imbalances during menopause, compounded by the natural ageing process, on bone health. Specifically, it examines the effects of increased bone turnover and focal bone balance on bone mass. A three-dimensional computational bone remodeling model was employed to simulate the response of the femur to habitual loads over a 19-year period, spanning premenopause, menopause, and postmenopause.

Contraction of Surfactant-Laden Pores.

The contraction of surfactant-laden pores at the microscale has implications for natural and technological processes ranging from the collapse of channels in lipid membranes to the stability of foams in the food processing industry. Despite their prevalence, our understanding of the mechanisms of pore contraction in the presence of surfactants remains unclear. These mechanisms have been challenging to study experimentally given the small length scale near the singularity and simulations capable of accurately characterizing the pore dynamics may help enhance our understanding of the process.