Publications by authors named "Diego M Avella Patino"

Article Synopsis
  • Minimally invasive esophagectomy (MIE) generally results in fewer postoperative complications compared to open esophagectomy (OE), but the risks might be influenced by how long the surgery takes.* -
  • Analyzing data from over 8,500 patients, researchers found that while MIE had a longer median operative time (402 minutes) than OE (321 minutes), the incidence of complications and 30-day mortality was lower for the MIE group.* -
  • Interestingly, when comparing short-duration OE surgeries to long-duration MIE surgeries, no significant differences in complications were observed, suggesting operative time may play a role in outcome consistency across approaches.*
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Purpose: Low-dose computed tomography (LDCT) screening of high-risk patients decreases lung cancer-related mortality. However, high false-positive rates associated with LDCT result in unnecessary interventions. To distinguish non-small-cell lung cancer (NSCLC) from benign nodules, in the present study, we integrated cellular liquid biomarkers in patients with suspicious lung nodules (lung cancer screening reporting and data system [Lung-RADS] 4).

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The epigenetic regulation of immune response involves reversible and heritable changes that do not alter the DNA sequence. Though there have been extensive studies accomplished relating to epigenetic changes in cancer cells, recent focus has been shifted on epigenetic-mediated changes in the immune cells including T cells, Macrophages, Natural Killer cells and anti-tumor immune responses. This review compiles the most relevant and recent literature related to the role of epigenetic mechanisms including DNA methylation and histone modifications in immune cells of wide range of cancers.

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