Publications by authors named "Diego L Barros"
Objective: We previously reported a case series of acute pancreatitis (AP) and macrophage activation syndrome (MAS) in childhood (cSLE) patients; however, there are no data regarding the comparison of AP and MAS in large populations of cSLE and adult SLE (aSLE).
Methods: A study included 362 cSLE and 1830 aSLE patients. MAS was diagnosed according to preliminary diagnostic guidelines and AP according to the presence of abdominal pain or vomiting associated to an increase of pancreatic enzymes and/or pancreatic radiological abnormalities.
Article Synopsis
- - This study analyzed chronic arthritis in childhood-onset systemic lupus erythematosus (cSLE) versus adult-onset systemic lupus erythematosus (aSLE), evaluating a total of 336 cSLE and 1,830 aSLE patients.
- - The findings showed similar frequencies of chronic arthritis in both groups (2.4% for cSLE and 3.8% for aSLE), but cSLE patients had a significantly earlier onset and presented more severe symptoms, such as higher joint involvement.
- - Various other clinical features, including rates of organ involvement (like hepatomegaly and nephritis), were notably higher in the cSLE population compared to a
Herpes zoster infection was significantly more often observed in children (10%, N = 362) than in adults (4%, N = 1830). At herpes zoster infection diagnosis, disease activity score (8 vs. 3, P = 0.
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