Health-related quality of life (HRQoL) loss associated with self-perceived anxiety/depression in seropositive rheumatoid arthritis.

Objective: To analyze the HRQoL loss associated with self-perceived anxiety/depression in patients with seropositive rheumatoid arthritis (RA).

Method: This secondary data analysis is based on a registry-based retrospective follow-up study of patients with seropositive RA treated between August 2014 and January 2023 in ARTMEDICA, Colombia. HRQoL loss and self-perceived anxiety/depression were defined as outcomes.

Global burden of young-onset Alzheimer's disease and other dementias: a secondary analysis of the global burden of disease study, 2019.

Unlabelled: The aging of the world population has led to an increase in the epidemiology and burden of Alzheimer's disease and other dementias.

Objective: To describe the global burden of young-onset Alzheimer's disease and other dementias by world region and income through a secondary analysis of the Global Burden of Disease Study 2019.

Methods: This is a descriptive cross-sectional ecological study.

Acceptance of Behavior Guidance Techniques in Pediatric Dentistry Between American and Colombian Parents.

To compare the degree of acceptance of behavior guidance techniques (BGT) in pediatric dentistry between American and Colombian parents. American parents (n=150) and Colombian parents (n=150) of children between three and 12 years of age undergoing pediatric dental treatment participated in this multicenter cross-sectional study. Parents viewed a video depicting 10 BGTs approved by the American Academy of Pediatric Dentistry and rated their acceptance on a visual analog scale.

Development of undergraduate students' diagnostic accuracy for the classification of molar incisor hypomineralization.

Introduction: One of the major difficulties with respect to molar incisor hypomineralization (MIH) is its classification and differentiation from other enamel development defects (EDDs). The aim of this study was to evaluate diagnostic accuracy in dental students to classify MIH as well as its differentiation from other EDDs by combining conventional theoretical classes and e-learning-assisted pre-clinical practices.

Methods: In this one-group pre-test and post-test study, 59 second-year students assessed 115 validated photographs using the MIH Index on the Moodle learning platform.

Altered B cell phenotype and CD27+ memory B cells are associated with clinical features and environmental exposure in Colombian systemic lupus erythematosus patients.

Background: B lymphocytes are dysregulated in Systemic Lupus Erythematosus (SLE) including the expansion of extrafollicular B cells in patients with SLE of African American ancestry, which is associated with disease activity and nephritis. The population of Colombia has a mixture of European, Native American, and African ancestry. It is not known if Colombian patients have the same B cell distributions described previously and if they are associated with disease activity, clinical manifestations, and environmental exposures.

Efficacy and safety of antipsychotics and antidepressants in the treatment of anorexia nervosa: a systematic review.

Introduction: The recommendations of the current guidelines are based on low quality evidence. Periodic updating is required, taking recent evidence into consideration.

Objective: To synthesise the best available clinical evidence on the efficacy and safety of second-generation antidepressants and antipsychotics in patients with anorexia nervosa.

Association between hypomineralization of deciduous and molar incisor hypomineralization and dental caries.

This study aimed to evaluate the association between the severity of hypomineralized second primary molars (HSPM), molar-incisor hypomineralization (MIH) and dental caries in children. 450 children between the ages of 6 and 7 years were included in this cross-sectional study. A calibrated examiner classified the enamel hypomineralizations and dental caries lesions using the MIH and HSPM and the Nyvad criteria, respectively.

Association Between Frequency and Severity of Dental Fluorosis and Molar Incisor Hypomineralization.

Objective: To assess the association between the frequency and severity of dental fluorosis (DF) and molar incisor hypomineralization (MIH) in a fluoridated salt region.

Study Design: In this retrospective cross-sectional study, we evaluated the buccal, occlusal/incisal, and palatal/lingual surfaces of first permanent molars and permanent incisors of 453 patients aged 13-16 years through intraoral standardized photographs. Two standardized examiners evaluated DF and MIH independently, utilizing the Thylstrup-Fejerskov (TF) index and the MIH index.

Efficacy of Transversus Abdominis Plane Block in the Reduction of Pain and Opioid Requirement in Laparoscopic and Robot-assisted Hysterectomy: A Systematic Review and Meta-analysis.

Objective:  To summarize the available evidence of TAP Block in efficacy in laparoscopic or robotic hysterectomy.

Data Sources:  We searched databases and gray literature for randomized controlled trials in which transversus abdominis plane (TAP) block was compared with placebo or with no treatment in patients who underwent laparoscopic or robot-assisted hysterectomy.

Method Of Study Selection:  Two researchers independently evaluated the eligibility of the selected articles.

Factors involved in time reduction between seizure relapses in patients with epilepsy attending emergency rooms in Medellín, Colombia.

Background: Seizure relapses are the leading cause of admission to emergency rooms (ER) in people with epilepsy.

Objective: To analyze administrative and clinical factors associated with the duration between seizure relapses in people with epilepsy admitted to the Neurological Institute of Colombia (Medellin) between July 2018 and July 2019.

Materials And Methods: A retrospective follow-up study of 156 patients over 18 years old, diagnosed with epilepsy, and treated for over a year.

Survival of stainless-steel crowns and composite resin restorations in molars affected by molar-incisor hypomineralization (MIH).

Background: Currently, there is no consensus on the superiority of any material for the restorative treatment of molars affected by molar-incisor hypomineralization (MIH).

Aim: To evaluate the survival of restorations with stainless-steel crown (SSC) or composite resin (CR) in first permanent molars affected by MIH for 24 months.

Design: In this retrospective cohort study, 61 CR and 54 SSC restorations placed on molars affected by MIH of patients, aged between 7 and 10, that were treated and overseen at a university dental clinic in the period of 2017-2020 were evaluated.

Efficacy and Safety of Antipsychotics and Antidepressants in the Treatment of Anorexia Nervosa: a Systematic Review.

Introduction: The recommendations of the current guidelines are based on low quality evidence. Periodic updating is required, taking recent evidence into consideration.

Objective: To synthesise the best available clinical evidence on the efficacy and safety of second-generation antidepressants and antipsychotics in patients with anorexia nervosa.

Does molar-incisor hypomineralization (MIH) affect only permanent first molars and incisors? New observations on permanent second molars.

Background: The second permanent molar plays an important role when considering extraction of first permanent molars severely affected by molar-incisor hypomineralization (MIH).

Aim: To assess the association between MIH and enamel hypomineralization of the second permanent molars in terms of presence and severity.

Design: In this retrospective cross-sectional study, permanent teeth were evaluated in 453 patients between the ages of 13 and 16 at a dental clinic, using intraoral photographs.

Greater caries-free survival of first permanent molars: Findings from a 7-year follow-up evaluation of a community-based oral health preventive program.

Background: The occlusal surface of the first permanent molar is the most frequently affected site by dental caries.

Aim: To assess the caries-free survival of first permanent molars in children participating in a community-based oral health preventive program.

Design: This was a retrospective study conducted on 426 children under 12 years of age, beneficiaries of a preventive program from 2009 to 2015, in El Cedro, Colombia.

Comparing definitions of spatial relations for the analysis of geographic disparities in mortality within a Bayesian mixed-effects framework.

Objective: To analyze the conceptual and technical differences between three definitions of spatial relations within a Bayesian mixed-effects framework: classical multilevel definition, spatial multiple membership definition and conditional autoregressive definition with an illustration of the estimate of geographic disparities in early neonatal mortality in Colombia, 2011-2014.

Methods: A registry based cross-sectional study was conducted. Births and early neonatal deaths were obtained from the Colombian vital statistics registry for 2011-2014.

Inter-regional metric disadvantages when comparing country happiness on a global scale. A Rasch-based consequential validity analysis.

Measurement confounding due to socioeconomic differences between world regions may bias the estimations of countries' happiness and global inequality. Potential implications of this bias have not been researched. In this study, the consequential validity of the Happy Planet Index, 2012 as an indicator of global inequality is evaluated from the Rasch measurement perspective.