Publications by authors named "Diego Ferla"
Article Synopsis
- COVID-19 is a disease caused by a virus called SARS-CoV-2 and can make people very sick or even worse.
- A study looked at a 42-year-old woman who had two kidney transplants and got really bad COVID-19, so she received special treatment with convalescent plasma.
- After the treatment, doctors saw that the amount of virus in her body decreased and her immune response improved, which is a good sign for her recovery.
Article Synopsis
- - Understanding how SARS-CoV-2 spreads in healthcare settings is important for developing effective interventions, especially considering the role of surface contamination (fomites) in transmission.
- - A year-long study in hospitals looked at SARS-CoV-2 RNA on surfaces, examining factors like surface dirtiness, the presence of a highly transmissible variant, and negative pressure systems in patient rooms.
- - Findings revealed that: (i) surface dirtiness did not correlate with SARS-CoV-2 RNA levels; (ii) the introduction of the Gamma variant increased contamination; (iii) negative pressure rooms had lower contamination levels; and (iv) most viral samples from contaminated surfaces were non-infectious.
The pandemic of coronavirus disease 2019 (COVID-19) is caused by a novel member of the family Coronaviridae, now known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Recent studies revealed the emergence of virus variants with substitutions in the spike and/or nucleocapsid and RNA-dependent RNA polymerase proteins that are partly responsible for enhanced transmission and reduced or escaped anti-SARS-CoV-2 antibodies that may reduce the efficacy of antibodies and vaccines against the first identified SARS-CoV-2 strains. In order to gain insight into the emergence and evolution of SARS-CoV-2 variants circulating in the South American region, a comprehensive phylogenetic study of SARS-CoV-2 variants circulating in this region was performed.
View Article and Find Full Text PDF