In situ effect of the combination of fluoridated toothpaste and fluoridated gel containing sodium trimetaphosphate on enamel demineralization.

Objective: This in situ study evaluated the effect of the association of low-F (4500μg F/g) gel containing TMP and FT (1100μg F/g) on enamel demineralization.

Methods: This crossover and double-blind study consisted of five phases of seven days each. Volunteers (n=12) wore palatal appliances containing four enamel blocks.