Publications by authors named "Diego Bastos Porto"
Article Synopsis
- A study was conducted to compare stroke incidences and mortality rates in critically ill COVID-19 patients from low-and middle-income countries (LMICs) and high-income countries (HICs).
- The results showed that stroke incidence was significantly higher in LMICs (35.7 per 1000 admitted-days) compared to HICs (17.6 per 1000 admitted-days), with patients from LMICs also facing higher mortality rates (43.6% vs. 29.2%).
- The findings highlight the need for better stroke diagnosis and healthcare resource allocation in LMICs, as both higher income status and the presence of stroke are associated with increased risk of death
Article Synopsis
- The study investigates the frequency and impact of neurological complications in critically ill COVID-19 patients, recognizing their potential link to fatal outcomes and modifiable risk factors.* -
- It is a secondary analysis of data collected from the COVID-19 Critical Care Consortium, focusing on adult ICU patients with confirmed COVID-19 and assessing various health aspects, including comorbidities and outcomes.* -
- Ethical approval has been obtained for the main study, allowing this analysis to proceed without additional approvals, with data being relevant for understanding patient prognosis and management in ICU settings.*
Introduction: Noninvasive neuromonitoring could be a valuable option for bedside assessment of cerebral dysfunction in patients with coronavirus disease-2019 (COVID-19) admitted to intensive care units (ICUs). This systematic review aims to investigate the use of noninvasive multimodal neuromonitoring in critically ill adult patients with COVID-19 infection.
Methods: MEDLINE/PubMed, Scopus, Cochrane, and EMBASE databases were searched for studies investigating noninvasive neuromonitoring in patients with COVID-19 admitted to ICUs.
Introduction: Neurological complications are frequent in patients with coronavirus disease-2019 (COVID-19). The use of non-invasive neuromonitoring in subjects without primary brain injury but with potential neurological derangement is gaining attention outside the intensive care unit (ICU). This systematic review and meta-analysis investigates the use of non-invasive multimodal neuromonitoring of the brain in non-critically ill patients with COVID-19 outside the ICU and quantifies the prevalence of abnormal neuromonitoring findings in this population.
View Article and Find Full Text PDFHyperinflammation in COVID-19 Obese Patients Treated With Tocilizumab: A Successful Case Series.
J Investig Med High Impact Case Rep
August 2021
The cytokine storm syndrome has been suggested as a mechanism in the pathophysiology of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2; COVID-19 [coronavirus disease 2019]) infection. Drugs such as tocilizumab, an interleukin-6 antagonist, have shown good results in other scenarios of hyperinflammatory state and might also be effective in COVID-19 disease. However, the best dosing regimen and the timing of infusion is currently unknown, specifically in obese patients.
View Article and Find Full Text PDFArticle Synopsis
- Stroke is a rare complication in ICU patients with COVID-19, with only 2.2% experiencing acute stroke during their hospital stay.
- Hemorrhagic stroke was linked to higher mortality rates, while ischemic stroke did not show the same increased risk of death.
- Patients with ischemic strokes had higher rates of conditions like diabetes and hypertension, especially compared to those without strokes.