Differences on Voice Acoustic Parameters between Colombian College Professors with and without Vocal Fatigue.

Aim: To determine which acoustic parameters may be associated with vocal fatigue among college professors in Bogotá-Colombia.

Method: This was a cross-sectional study including 27 voice samples of college professors.

Results: A gender analysis showed that mean fundamental frequency increased significantly among men and women who reported vocal fatigue compared with the those without fatigue (138.

RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs.

Background: There is a need for more powerful methods to identify low-effect SNPs that contribute to hereditary COPD pathogenesis. We hypothesized that SNPs contributing to COPD risk through cis-regulatory effects are enriched in genes comprised by bronchial epithelial cell (BEC) expression patterns associated with COPD.

Methods: To test this hypothesis, normal BEC specimens were obtained by bronchoscopy from 60 subjects: 30 subjects with COPD defined by spirometry (FEV1/FVC < 0.