Publications by authors named "Didier Quilliot"

Article Synopsis
  • Undernutrition is common in patients with inflammatory bowel diseases (IBD), with a study showing a prevalence rate of 25.8%, including moderate and severe cases.
  • The study assessed 434 IBD patients, revealing that 81.1% had experienced undernutrition since their diagnosis, with a notable average weight loss of 14.5%.
  • Factors linked to undernutrition included total food category exclusions and active disease, while a longer duration of IBD was associated with a lower prevalence of undernutrition.
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Background: Radiation-induced nausea and vomiting have mutiple clinical consequences: delay or refusal of irradiation (decreased antineoplastic efficacy of irradiation), altered quality of life, dehydration, malnutrition, interruption of treatment, decompensation of comorbidities and aspiration. These guidelines aim at defining good clinical practices for management of radiation-induced nausea and vomiting (RINV).

Methods: AFSOS, SFRO, SFH, SFNEP, SFCE and GFRP applied an expert consensus methodology to propose updated guidelines.

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Purpose: The primary objective was to evaluate bone fragility on dual X-ray absorptiometry (DXA) in patients with obesity before and 2 years after bariatric surgery. The secondary objective was to identify risk factors for the development of a bone mineral density ≤ -2 SD at 2 years.

Methods: This descriptive study included patients with obesity who underwent DXA before and 2 years (±6 months) after bariatric surgery.

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Article Synopsis
  • Renal dysfunction frequently occurs in patients with cirrhosis, either due to acute illness or the progression of liver disease, but comprehensive evaluations of renal function markers have not been thoroughly studied.
  • A retrospective study was conducted on hospitalized cirrhosis patients from January 2021 to June 2023, involving a detailed assessment of renal function across 43 parameters.
  • The findings revealed that most patients exhibited renal abnormalities, with significant overestimations in estimated glomerular filtration rates compared to measured creatinine clearance, highlighting the importance of multiparametric assessments for properly evaluating kidney function in these patients.*
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Article Synopsis
  • The main treatment for short bowel syndrome is getting nutrition at home through a special method called parenteral nutrition, but patients need to follow strict rules to avoid problems.
  • Some patients prefer to receive help from nurses rather than being completely responsible for their care, even though doctors encourage everyone to learn how to do it themselves.
  • Interviews with patients showed that while some enjoy having more control over their care, others feel safer and more comfortable when a nurse visits them regularly.
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Unlabelled: Screening for sarcopenia is a growing public health issue since associated with functional alterations and an increase in morbidity and mortality.

Objective: To analyze the prevalence of decreased muscle strength (dynapenia) in patients aged 18 to 74 in community medicine, as measured in the general practitioner's office, and to assess the prevalence of undernutrition in this population.

Method: Muscle strength was measured with a Hand Grip (HG) dynamometer according to European recommended thresholds and French guidelines.

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Background & Aims: There are sparse data regarding the rate of catheter salvage and long-term effectiveness of antibiotic lock treatment outcome after central line-associated bloodstream infections (CLABSI). Objectives were to analyze the effectiveness of central venous catheter (CVC) rescue strategy and its impact on catheter lifespan. Secondary objective included effectiveness of taurolidine+4% citrate in primary prevention, compared to a secondary prevention strategy, by analyzing infection incidence during two successive periods.

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Background: Patients with inflammatory bowel disease (IBD) consider that their diet is important for controlling symptoms and frequently ask their physician for additional guidance on this matter. The objectives of the present study of patients with IBD were to characterize the prevalence of exclusion diets and fasting and to identify associated risk factors.

Methods: Using an anonymous questionnaire, we screened patients attending our IBD nutrition clinic between November 2021 and April 2022 for exclusion diets.

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Introduction: The objectives were to evaluate bone fragility on computed tomography (CT) in patients with obesity before and 2 years after bariatric surgery and to identify risk factors for a decrease in the scanographic bone attenuation coefficient of the first lumbar vertebra (SBAC-L1).

Materials And Methods: Patients with obesity who underwent bariatric surgery and CT before and 2 years (± 6 months) after bariatric surgery were included. SBAC-L1 was measured on CT with a fracture threshold at 145 HU.

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The primary objective was to evaluate bone fragility prevalence on dual X-ray absorptiometry (DXA) and computed tomography (CT) in patients with severe obesity. The secondary objective was to evaluate the risk factors for bone fragility. This monocentric study was conducted in patients with grade 2 and 3 obesity.

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Purpose: Psychological disorders, early-age psychological traumas and eating disorders may contribute to the development of severe obesity in vulnerable individuals. Resilience may serve a protective role against binge eating disorder or depression. The current study aimed to investigate the relationship between adverse childhood experiences (ACE), resilience, and current psychological disorders.

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Although central venous catheter (CVC)-related thrombosis (CRT) is a severe complication of home parenteral nutrition (HPN), the amount and quality of data in the diagnosis and management of CRT remain low. We aimed to describe current practices regarding CVC management in French adult and pediatric HPN centers, with a focus on CVC obstruction and CRT. Current practices regarding CVC management in patients on HPN were collected by an online-based cross-sectional survey sent to expert physicians of French HPN centers.

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NUTRITIONNAL COMPLICATIONS AND PATIENTS FOLLOW-UP AFTER BARIATRIC SURGERYBariatric surgery is the most consistently effective method for sustained weight reduction and can result in a substantial improvement in overall survival in patients with severe obesity. Complex mechanisms underlying metabolic benefits could also drive preventable, but potentially life-threatening, long-term nutritional complications. Consequently, physicians should be familiar with the lifelong monitoring of patients after bariatric surgery and the potential long-term complications in this paradoxical situation where the long-awaited weight loss can lead to severe nutritional complications.

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Obesity results from a temporary or prolonged positive energy balance due to an alteration in the homeostatic feedback of energy balance. Food, with its discriminative and hedonic qualities, is a key element of reward-based energy intake. An alteration in the brain reward system for highly palatable energy-rich foods, comprised of fat and carbohydrates, could be one of the main factors involved in the development of obesity by increasing the attractiveness and consumption of fat-rich foods.

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Background: Chronic heart failure (CHF) is one of the most common causes of mortality in industrialized countries despite regular therapeutic advances. Numerous factors influence mortality in CHF patients, including nutritional status. It is known that malnutrition is a risk factor for mortality, whereas obesity may play a protective role, a phenomenon dubbed the "obesity paradox".

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Sugar overconsumption is linked to a rise in the incidence of noncommunicable diseases such as diabetes, cardiovascular diseases, and cancer. This increased incidence is becoming a real public health problem that is more severe than infectious diseases, contributing to 35 million deaths annually. Excessive intake of free sugars can cause many of the same health problems as excessive alcohol consumption.

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Unlabelled: Post-acute consequences of COVID-19, also termed long COVID, include signs and symptoms persisting for more than 12 weeks with prolonged multisystem involvement; most often, however, malnutrition is ignored.

Method: The objective was to analyze persistent symptoms, nutritional status, the evolution of muscle strength and performance status (PS) at 6 months post-discharge in a cohort of COVID-19 survivors.

Results: Of 549 consecutive patients hospitalized for COVID-19 between 1 March and 29 April 2020, 23.

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Article Synopsis
  • A study identified 14 low-frequency genetic variants linked to body mass index (BMI) in a large group of mostly European individuals.
  • The research aimed to evaluate how two genetic scores (GS) related to obesity risk, BMI changes before and after lifestyle interventions, and outcomes after bariatric surgery.
  • Findings showed that while the risk GS didn't correlate with severe obesity or pre-intervention BMI, BMI-decreasing variants were less common in obese individuals; however, the protective GS led to more significant BMI decreases after bariatric surgery and influenced the likelihood of weight regain.
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Aim: Hospital food provision is subject to multiple constraints (meal production, organization, health safety, environmental respect) which influence the meal tray offered to the patient. Multiple diets can add complexity and contribute to non-consumption of the meal. To avoid undernutrition, it appeared necessary to propose guidelines for foods and diets in hospitals.

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Unlabelled: The nutritional sequelae of COVID-19 have not been explored in a large cohort study.

Objectives: To identify factors associated with the change in nutritional status between discharge and 30 days post-discharge (D30). Secondary objectives were to determine the prevalence of subjective functional loss and severe disability at D30 and their associated factors.

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Hypomagnesemia and hypermagnesemia could have serious implications and possibly lead to progress from a mild form to a severe outcome of Covid-19. Susceptibility of subjects with low magnesium status to develop and enhance this infection is possible. There is little data on the magnesium status of patients with Covid-19 with different degrees of severity.

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Objective: After Roux-en-Y gastric bypass (RYGB), postprandial hyperinsulinemic hypoglycemia (PPHH) is particularly critical because of the risk of trauma. The aim of this study was to assess the incidence and identify risk factors for symptomatic PPHH.

Methods: Patients with RYGB were classified into moderate PPHH (MH) or severe hypoglycemia (SH), which is defined as patients with neuroglycopenic symptoms.

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