Publications by authors named "Didi Yang"
Novel biocompatible palladium nanoparticles (Pd-NPs) have been prepared by microorganisms via Y-4. It was demonstrated that ultrasonication treatment of biologically reduced Pd-NPs impart a much higher absorption in NIR regions and a better photothermal conversion efficiency to the material. The as-prepared material showed excellent biocompatibility and antibacterial activity under NIR irradiation.
View Article and Find Full Text PDFBioactivity of umbilical cord blood dendritic cells and anti-leukemia effect.
Int J Clin Exp Med
January 2016
Objective: We investigated the effect of umbilical cord blood dendritic cells (DCs) on in vitro proliferation, immunophenotypes and levels of homologous cytokine-induced killer cells (CIK) and the toxicity on leukemia cells.
Method: Mononuclear cell-induced DC-CIK cells derived from umbilical cord blood were collected and co-cultured in the proportion of 1:5. Cord blood CIK cells or peripheral blood DC-CIK cells were used as control.
Influence of dendritic cells on biological activity of the homologous CIK cells and its anti-leukemia effect in vitro.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2010
Article Synopsis
- The study explored how cord blood dendritic cells (DCs) affect the growth and function of homologous cytokine-induced killer (CIK) cells, particularly against leukemia cells.
- Results showed that CIK cells co-cultured with cord blood DCs had significantly higher proliferation rates and changes in immunophenotype compared to those cultured alone or with peripheral blood DCs.
- Additionally, the levels of key cytokines (IL-12, IFN-γ, TNF-α) were notably higher in cord blood DC-CIK cell cultures, and these cells exhibited superior anti-leukemia activity compared to other groups.
Biological activity of DC-CIK cells and its effect against leukemia cells in vitro.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
October 2008
This study was aimed to investigate the effect of dendritic cells (DC) on the proliferation capability, immunophenotype changes, level of secreted cytokines and activity against leukemia of cytokine-induced killer (CIK) cells in vitro. DCs and CIK cells were induced from peripheral blood mononuclear cells of healthy volunteers. They were co-cultured meanwhile CIK cells were cultured alone as controls.
View Article and Find Full Text PDFObjective: To establish a serum-free culture system of dendritic cells (DCs) from chronic myeloid leukemia (CML) cells so that DCs vaccine may be applied to the adoptive immunotherapy of CML in the near future.
Methods: Fetal calf serum, serum-free medium and autologous serum were used for culture of DCs. The usage of cytokines was classified into two groups: group A (stem cell factor, granulocyte/macrophage colony-stimulating-factor, tumor necrosis factor-alpha and interleukin-4) and group B (granulocyte/macrophage colony-stimulating-factor, tumor necrosis factor-alpha and interleukin-4).