Publications by authors named "Didem Sahin-Eroglu"

Backgrounds: Adult-onset Still's Disease (AOSD) is a systemic inflammatory disorder. There is no definitive AOSD activity indicator. Two of the currently used disease activity scores are the Modified Pouchot Activity Score (mPoS), and Systemic Feature Score (SFS).

View Article and Find Full Text PDF
Article Synopsis
  • ANCA-associated vasculitis (AAV) is a rare disease that makes blood vessels inflamed and can lead to serious infections.
  • The study looked at 84 patients with AAV to find out what increases the risk of getting serious infections that need hospitalization.
  • It found that having lung and kidney problems, being older than 65, and having high levels of a protein called C-reactive protein (CRP) were important factors that made infections more likely.
View Article and Find Full Text PDF

Background: Systemic sclerosis (SSc) is a chronic systemic disease characterized by vascular damage, autoimmunity, and fibrosis in the skin and internal organs. In this study, we tried to determine the causes of severe infection in patients with SSc and to reveal the factors associated with severe infection.

Methods: We retrospectively examined 214 SSc patients between January 2010 and August 2020.

View Article and Find Full Text PDF
Article Synopsis
  • This study aimed to compare the occurrence of Helicobacter pylori infection in rheumatoid arthritis (RA) patients who experienced gastrointestinal intolerance due to methotrexate (MTX) and those who did not.
  • Out of 390 analyzed patients, 41% exhibited MTX-related gastrointestinal intolerance, with higher rates of H. pylori and inflammation found in that group.
  • Logistic regression showed that both the presence of H. pylori and the use of specific biologic medications were significantly linked to the gastrointestinal issues caused by MTX.
View Article and Find Full Text PDF

Objective: To demonstrate the effects of rituximab (RTX) in patients with rheumatoid arthritis-related interstitial lung disease (RA-ILD).

Methods: A total of 165 patients who used RTX for the management of rheumatoid arthritis were retrospectively scrutinised. Among these, 26 patients diagnosed with RA-ILD were analysed (61.

View Article and Find Full Text PDF

Objective: In this study, it was aimed to reveal the hospitalization reasons for patients diagnosed with primary Sjögren syndrome (pSS) and potentially associated factors in a tertiary health center.

Method: One hundred and sixty-three pSS patients who regularly attended their follow-ups between January 2010 and May 2021 were included in the study. These patients' reasons for hospitalization, duration of hospitalization, and numbers of presenting to the hospital were recorded.

View Article and Find Full Text PDF
Article Synopsis
  • The study looks at the demographic and clinical characteristics of vascular involvement in patients with Behçet's Syndrome (BS), analyzing data from 2,118 patients to find associations with vascular events.
  • About 14.8% of patients had isolated superficial thrombophlebitis (ST), while 85.2% experienced major vascular events, with the most common being deep venous thrombosis.
  • Male sex was found to significantly increase the risk of vascular involvement, and the presence of ST was identified as the strongest risk factor for major vascular events.
View Article and Find Full Text PDF

Background: Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by microangiopathy, inflammation, fibrosis. Interstitial lung disease (ILD) is common among SSc patients.

Objective: This study aims to define the clinical, laboratory, and serologic characteristics of SSc patients with ILD and to present the frequency of chest computed tomography features.

View Article and Find Full Text PDF

Objective: To describe the clinical characteristics of neuro-Behçet's syndrome (NBS) and to define the factors associated with relapses and poor outcome.

Methods: Among 2118 patients with Behçet's syndrome who fulfilled the international study group criteria, 208 (9.8%) patients had NBS.

View Article and Find Full Text PDF

Objective: Calprotectin is an inflammatory biomarker which assesses disease activity in rheumatoid arthritis (RA). The objective of this study was to test whether serum calprotectin is associated with clinical and ultrasonographic disease activity in patients with RA, and to analyse its predicting value for disease activity evaluation despite normal C-Reactive protein (CRP) levels.

Methods: We included 80 patients with RA and 30 healthy subjects.

View Article and Find Full Text PDF

Background: High mobility group box- 1 (HMGB- 1) is a nuclear protein acting as a proinflammatory molecule. The serum HMGB- 1 levels were found elevated in chronic inflammatory diseases. In this cross-sectional study, serum HMGB- 1 levels in Behcet's disease (BD) patients and healthy controls (HC) were studied.

View Article and Find Full Text PDF

Objectives: Existence of panel reactive antibodies is the limiting step in both solid-organ and hematopoietic stem cell transplantation. There are hypotheses related to panel reactive antibody formation, but there is no knowledge about its formation in acute leukemia at diagnosis and during the chemotherapy period, in which there is a strong myelosuppression and immunosuppression. We aimed to determine the panel reactive antibodies positivity in acute leukemia patients at diagnosis and during the entire therapy period, including stem cell transplantation.

View Article and Find Full Text PDF

Objective: To report the clinical characteristics of pulmonary artery involvement (PAI) in patients with Behçet's syndrome (BS) and to define the predictors of relapses.

Methods: We performed retrospective analysis of BS patients with PAI who fulfilled international study group criteria. Among 460 patients with vascular Behçet's syndrome (VBS), 66 were diagnosed with PAI.

View Article and Find Full Text PDF

Introduction/objectives: Primary Sjögren syndrome (pSS) is usually encountered between the fourth and sixth decades. It is known that the age of onset in autoimmune diseases may affect the clinical features. In this study, we aimed to investigate the clinical and laboratory characteristics of early onset pSS patients.

View Article and Find Full Text PDF