Diet restriction in migraine, based on IgG against foods: a clinical double-blind, randomised, cross-over trial.

Introduction: It is well-known that specific foods trigger migraine attacks in some patients. We aimed to investigate the effect of diet restriction, based on IgG antibodies against food antigens on the course of migraine attacks in this randomised, double blind, cross-over, headache-diary based trial on 30 patients diagnosed with migraine without aura.

Methods: Following a 6-week baseline, IgG antibodies against 266 food antigens were detected by ELISA.