Calcifying epithelial odontogenic tumor: a case report.

Calcifying epithelial odontogenic tumor (CEOT) is a rare benign lesion. A case of CEOT in the left mandible of a 46-year-old man is presented. This case is exceptionally unusual because it was left untreated for 10 years, indicating in some way the course of the tumor.

Adult laryngeal rhabdomyosarcoma: is aggressive treatment justified in all cases? A case report and review of the literature.

Background: Adult laryngeal rhabdomyosarcomas are rare tumours commonly treated by laryngectomy.

Case Report: We present a case of subglottic laryngeal rhabdomyosarcoma in an elderly woman, treated by endoscopic resection.

Conclusion: Despite the fact that this tumour is traditionally treated aggressively, this approach is not supported by the literature.

Immunohistochemical assessment of basement membrane components in colorectal cancer: prognostic implications.

Loss of basement membrane integrity during neoplastic invasion may have some direct prognostic significance, which is worth investigating. We studied 151 cases of colorectal adenocarcinomas retrospectively. The aim of the study was to investigate the immunohistochemical expression as well as the distribution of laminin and collagen IV within the basement membranes of cancer cell formations.

In situ expression of E-selectin and intercellular adhesion molecule-1 in chronic inflammatory diseases of the gastrointestinal tract.

Aim: The study of cell adhesion molecules contributes to our understanding of the inflammatory mechanisms which include the endothelial activation of newly formed or pre-existing vessels, the increase of inflammatory cells' adhesive capability and their migration into perivascular tissues. The aim of the present study was to investigate the local presence and the extent of expression of E-selectin and intercellular adhesion molecule-1 (ICAM-1) in the mucosa of patients with chronic gastritis, chronic inflammatory bowel disease, and controls, as well as to identify possible correlations between in situ expression of the above adhesion molecules and degree of inflammatory activity or therapeutic response.

Design: In cryostat tissue sections we examined the immunohistochemical expression and localization of E-selectin and the intercellular adhesion molecule-1 (ICAM-1).

Nm-23, c-erbB-2, and progesterone receptor expression in invasive breast cancer: correlation with clinicopathologic parameters.

Downregulation of nm-23 antimetastasis gene has been associated with disease progression in some human tumors. NPD kinase A is the product of the H1 isotype of the nm23 gene and its value as a marker of metastatic potential is well worth investigating. The expression of the nm23-H1 gene peptide was immunohistochemically evaluated in 191 primary mammary cancer tissues.

Non-small cell lung cancer: c-erbB-2 overexpression correlates with low angiogenesis and poor prognosis.

Tumour angiogenesis is an important prognostic factor in non-small cell lung cancer. Recently, EGFR and c-erbB-2 protein was found to regulate cell adhesion and the invasive growth of cancer through its association with the cadherin-catenin complex. The role of c-erbB-2 protein in cell migration has been also reported.