Publications by authors named "Dibekoglu C"

Article Synopsis
  • The study evaluated the effectiveness of sulfasalazine in preventing and treating acute respiratory distress syndrome (ARDS) caused by sepsis in rats.
  • Forty male Wistar albino rats were divided into four groups: a control group, a septic group, a placebo group, and a group treated with sulfasalazine.
  • Results showed that the sulfasalazine group had significantly lower levels of inflammatory markers and improved lung function compared to the placebo group, indicating its potential as a treatment for ARDS.
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Surgical treatments of advanced tumors have expanded in the last two decades as a result of ad-vances in surgical techniques, advanced interventional radiology methods, improved intensive care unit settings and increased overall life expectancy. Advanced liver tumors represent a broad category from various malignancies such as liver metastasis or native liver tumors. Not uncom-monly these tumors are not amenable to curative treatment and require down-staging, or local control at the initial diagnosis.

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It has been hypothesized that short appendices increase intraluminal pressure more rapidly and perforate more frequently than long appendices. Two hundred seventy-seven adult patients were retrospectively analyzed and underwent an appendectomy between January 2015 and August 2021. Data extracted from patient records included sex, age, time from admission to operation (hospital interval), weekday or weekend operation time, and operative and pathological findings.

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Purpose: To evaluate the ameliorative effect of mesenchymal stem cells (MSCs) on acetic acid colitis model via Nrf2/HO-1 pathway in rats.

Methods: In this study, 30 rats were divided into three groups. Acute colitis was induced by rectal administration of 4% solution of acetic acid.

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Article Synopsis
  • The study aimed to evaluate the effectiveness of givinostat in treating ulcerative colitis in a rat model induced by acetic acid.
  • Thirty male rats were divided into three groups: one group received saline, and the other received givinostat, allowing for comparison of treatment effects on colitis.
  • Results indicated that givinostat significantly reduced inflammatory markers and improved histopathological outcomes compared to the saline group, suggesting its potential as a therapeutic option for colitis.
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Purpose: The variation of multiple bile ducts in a living donor graft is not infrequent; however, the literature on the impact of the number of bile ducts on postoperative biliary complications is scarce. We investigated whether the number of biliary duct anastomoses affects the rate of postoperative biliary complications in patients undergoing living donor liver transplantation (LDLT).

Materials And Methods: Between January 2016 and January 2018, all patients who underwent LDLT were reviewed.

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Background: The degree of liver steatosis is an important factor for donor selection in living donor liver transplantation. Multidetector computed tomography (MDCT) has long been used in many transplantation centers to determine donor liver steatosis. Noninvasive scoring methods based on laboratory tests have been investigated as potential methods for altering liver biopsy and imaging techniques in evaluating the liver steatosis.

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Aim Of The Study: To analyse the incidence of appendiceal neuroendocrine neoplasms in appendectomy specimens and establish the epidemiological and histopathological features, treatment, and clinical course.

Material And Methods: Between 2004 and 2013, 975 patients who underwent appendectomy in Ankara Oncology Education and Research Hospital were retrospectively analysed.

Results: Neuroendocrine neoplasm was detected in the nine of 975 (0.

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Aim: To analyse the incidence of bone fracture of breast cancer patients with isolated bone metastasis and its effect on survival. We tried to find an answer to the question of "Can the development of bone fracture be predicted?"

Methods: Between 1993-2006, 139 breast cancer patients with isolated bone metastasis were examined. Patients were divided into two groups depending on the development of pathologic bone fracture.

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Background: The aim of this study was to compare gastrointestinal complications and associated risk factors among patients undergoing cardiac surgery using off- and on-pump revascularization techniques.

Methods: A total of 1146 adult patients who underwent coronary artery surgery during a 6-year period were evaluated retrospectively. Group 1 consisted of 546 patients operated using off-pump techniques and group 2 consisted of 600 cases operated with cardiopulmonary bypass.

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Objective: To investigate the changes in intestinal nitric oxide (NO) and myeloperoxidase (MPO) concentrations, the rate of endotoxaemia, and intestinal mucosal structure in rats after irradiation of the abdomen and to find out the effect of Nomega-nitroarginine methyl ester (L-NAME) inhibition NO synthesis.

Setting: Medical school, Turkey.

Design: Experimental study.

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