Publications by authors named "Diba Saeidi"
Background: Interferon-beta (IFN-β) is a cytokine with a wide range of biological and pharmaceutical applications, including multiple sclerosis (MS), cancer, some autoimmune disorders, and viral infectious diseases. Thus, many studies have been performed to develop novel strategies for the high-yield production of functional IFN-β in a cost-effective approach. Here, we aimed to improve the intracellular expression of IFN-β-1a in .
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- A systematic review and meta-analysis were conducted to assess the accuracy of ultrasonography for diagnosing elbow fractures in children, as previous studies have shown mixed results.
- The analysis included 648 studies with 1,000 patients, revealing a pooled sensitivity of 95% and specificity of 87%, indicating that ultrasonography is generally effective.
- Despite promising findings, the authors caution that the studies had limitations and suggest the need for future high-quality research to better standardize the use of ultrasonography in clinical settings.
Article Synopsis
- - The study evaluates the Ottawa Knee Rule (OKR) for diagnosing fractures in knee trauma cases, aiming to improve accuracy and reduce unnecessary radiation exposure from radiography.
- - A systematic review of 18 studies involving 6,702 patients revealed that OKR has a sensitivity of 98% and a specificity of 43% for detecting fractures.
- - The findings suggest that OKR could potentially decrease unnecessary radiography and associated costs, although more high-quality research is needed to confirm these benefits.