Publications by authors named "Diba Khan"

Public health practitioners rely on timely surveillance data for planning and decision-making; however, surveillance data are often subject to delays. Epidemic trend categories, based on time-varying effective reproductive number (R) estimates that use nowcasting methods, can mitigate reporting lags in surveillance data and detect changes in community transmission before reporting is completed. CDC analyzed the performance of epidemic trend categories for COVID-19 during summer 2024 in the United States and at the state level in New Mexico.

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Background: In 2012, the US Preventive Services Task Force recommended against prostate cancer screening using the PSA test for all age groups. In 2018, the US Preventive Services Task Force's recommendation shifted from a "D" (not recommended) to a "C" (selectively offering PSA-based screening based on professional judgment and patient preferences) in men ages 55 to 69. Limited reliable county-level prostate cancer screening data are available for cancer surveillance purposes.

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Mortality surveillance systems can have limitations, including reporting delays, incomplete reporting, missing data, and insufficient detail on important risk or sociodemographic factors that can impact the accuracy of estimates of current trends, disease severity, and related disparities across subpopulations. The Centers for Disease Control and Prevention used multiple data systems during the COVID-19 emergency response-line-level case‒death surveillance, aggregate death surveillance, and the National Vital Statistics System-to collectively provide more comprehensive and timely information on COVID-19‒associated mortality necessary for informed decisions. This article will review in detail the line-level, aggregate, and National Vital Statistics System surveillance systems and the purpose and use of each.

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On January 31, 2020, the U.S. Department of Health and Human Services (HHS) declared, under Section 319 of the Public Health Service Act, a U.

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Article Synopsis
  • - Early in the COVID-19 pandemic, the CDC adapted its existing surveillance system to monitor cases and deaths efficiently, implementing a new aggregate case surveillance system for quicker data collection and emergency response.
  • - This new system enabled the CDC to gather and analyze COVID-19 data at national, state, and county levels, using innovative methods like web scraping and algorithms to streamline data accuracy and validation.
  • - The review emphasizes the importance of having a robust aggregate surveillance system ready for future health emergencies, providing near-real-time data to enhance response efforts beyond traditional individual case reporting.
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Article Synopsis
  • - During the COVID-19 pandemic, the CDC implemented an aggregate case and death surveillance (ACS) system to effectively track cumulative COVID-19 data, supplementing traditional reporting methods.
  • - As public health jurisdictions updated their historical data, the CDC developed a manual process for updating the ACS dataset to improve the accuracy of reported case and death numbers.
  • - By March 2022, the CDC began integrating data from three jurisdictions via application programming interfaces (APIs), which streamline data transfer and may enhance emergency response efficiency moving forward.
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The objective of this analysis was to explore temporal and spatial variation in teen birth rates TBRs across counties in the USA, from 2003 to 2012, by using hierarchical Bayesian models. Prior examination of spatiotemporal variation in TBRs has been limited by the reliance on large-scale geographies such as states, because of the potential instability in TBRs at smaller geographical scales such as counties. We implemented hierarchical Bayesian models with space-time interaction terms and spatially structured and unstructured random effects to produce smoothed county level TBR estimates, allowing for examination of spatiotemporal patterns and trends in TBRs at a smaller geographic scale across the USA.

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Teen birth rates have evidenced a significant decline in the United States over the past few decades. Most of the states in the US have mirrored this national decline, though some reports have illustrated substantial variation in the magnitude of these decreases across the U.S.

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Background: In the US, black infants remain more than twice as likely as white infants to die in the first year of life. Previous studies of geographic variation in infant mortality disparities have been limited to large metropolitan areas where stable estimates of infant mortality rates by race can be determined, leaving much of the US unexplored.

Methods: The objective of this analysis was to describe geographic variation in county-level racial disparities in infant mortality rates across the 48 contiguous US states and District of Columbia using national linked birth and infant death period files (2004-2011).

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Multiple imputation is a popular approach to handling missing data. Although it was originally motivated by survey nonresponse problems, it has been readily applied to other data settings. However, its general behavior still remains unclear when applied to survey data with complex sample designs, including clustering.

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The probability that mortality from certain causes exceeds high thresholds is addressed. An out-of-sample fusion method is presented where an original real data sample is fused or combined with independent computer-generated samples in the estimation of exceedance probabilities assuming a density ratio model. Since the size of the combined sample of real and artificial data is larger than that of the real sample, the fused sample produces short confidence intervals relative to traditional methods.

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Over the past several years, the death rate associated with drug poisoning has increased by over 300% in the U.S. Drug poisoning mortality varies widely by state, but geographic variation at the substate level has largely not been explored.

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Background: Drug poisoning mortality has increased substantially in the U.S. over the past 3 decades.

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