Potential for a large-scale newborn screening strategy for sickle cell disease in Mali: A comparative diagnostic performance study of two rapid diagnostic tests (SickleScan® and HemotypeSC®) on cord blood.

Sickle cell disease (SCD) is a life-threatening disease requiring reliable early diagnosis. We assessed the acceptability and diagnostic performances of two rapid diagnostic tests (RDTs) to identify SCD (HbSS, HbSC, HbS/β-thalassaemia) or SCD carrier (HbS/HbC) in a pilot SCD newborn screening (NBS) strategy in Mali. All consenting delivering women were offered SCD NBS using cord blood sampling on two RDTs (SickleScan® and HemotypeSC®) compared to the high-performance liquid chromatography (HPLC) gold standard to detect SCD states.

[Medico-Surgical treatment of mycetoma in the Somine Dolo hospital of Mopti (Mali)].

Objective: The objective of this study was to describe the epidemiological and clinical aspects as well as the therapeutic methods of mycetomical lesions.

Material And Methods: This was a longitudinal retrospective study, which included all patients treated for mycetoma from January 2016 to December 2018 including two years of recruitment and one year of monitoring (2019). The study concerned 19 patients who were hospitalized and treated in the department of surgery.

[Recurrences of precancerous lesions after conservative treatment: Operational results after a decade in Abidjan].

Objectives: There remains a significant risk of recurrence of intraepithelial neoplasia regardless of the type of conservative treatment. The aim's work is to assess this rate.

Methods: All women's consenting who had received conservative treatment at the sites identified since for more than 12 months were included in this multicenter cross-sectional study.

[Foreskin Cyst After Circumcision At The Hospital Of Sikasso (MALI)].

Cyst scar post circumcision of the stump of the prepuce is pathology of which we have not found any cases in the literature. The circumcision traditional is still practiced in our regions with its attendant complications, in particular, the high section, the whole or part of the gland, infections. The case we report concerns a patient 24 years of age, having a large cyst of 8cm diameter, evolving for the past 17 years.

[Consent To The Episiotomy About 331 Cases At The Health Reference Center Of The "Commune I" Of The District Of Bamako].

Unlabelled: Episiotomy is a surgical act performed during childbirth to widen the vaginal opening; like any other medical procedure, its benefits and risks must be made known to patients in accordance with the legal and regulatory provisions of each country.The principle of immunity of the human body makes that the consent in the care is the keystone of the doctor-patient relationship, this consent is the first legitimization of the medicalact. The consent has to «be free and lit» as far as the decision of the patient must be taken without any constraint or pressure having obtained all the necessary information.

[Major Causes Of Limb Amputations At The Hospital In Sikasso].

Introduction: In this study, we aimed to determine the major causes of limb amputations to improve its treatment.

Patients And Methods: We conducted a-18 month prospective study from March 2015 to September 2016 at the Hospital of Sikasso, a hospital of second reference in Mali.

Results: We carried out 50 major limb amputations including 25 men and 25 women aged 38.