Publications by authors named "Dianny Martinez"
Objective: To characterize carbapenemase-producing isolated from patients treated at a hospital in Cumaná, Sucre, Venezuela.
Methods: This was a retrospective study conducted at the general hospital in Cumaná where 58 strains were analyzed for resistance to antimicrobials, specifically carbapenems, in January - June 2015. Production of metallo-β-lactamases and serine carbapenemases was determined by the double-disc synergy test, using EDTA-sodium mercaptoacetic acid and 3-aminophenyl boronic acid discs, respectively.
Article Synopsis
- The study examines the rise of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa strains in a hospital in Venezuela, highlighting their potential threat to public health.
- Most of the analyzed strains showed virulence factors and mobility, with a significant increase in MDR and XDR strains from 2009 to 2016, linked to specific genes and resistance traits.
- The findings suggest a strong connection between MDR/XDR strains and severe clinical conditions, emphasizing risks for patients and the possibility of infection spread within the community.
[qnr genes in Enterobacteriaceae isolated from at a hospital in Venezuela].
Rev Chilena Infectol
April 2018
Article Synopsis
- The study investigates the rising issue of enterobacteria in Venezuela that are resistant to quinolone antibiotics, focusing on the role of qnr genes in this resistance.
- Researchers conducted antimicrobial susceptibility tests and PCR to identify these genes, discovering that 33.6% of the isolates carried the qnrB gene and a small fraction carried qnrA.
- The findings suggest a significant presence of qnr genes on transferable plasmids, necessitating a careful strategy for antibiotic use to prevent further development of resistant bacterial strains.
In order to study the clonal relationship and blaKPC gene detection in clinical isolates of Klebsiella pneumoniae resistant to carbapenems, we analyzed 22 clinical isolates of K. pneumoniae with resistance to imipenem and/ or meropenem, isolated in the laboratory of bacteriology at the University Hospital "Antonio Patricio de Alcalá" (HUAPA) from the Cumana city, Sucre state, Venezuela, for a period of five consecutive years. Susceptibility to different antimicrobials was determined, and the presence of carbapenemases was detected by modified Hodge method, phenyl boronic acid synergy and combination discs.
View Article and Find Full Text PDFBesides the importance of Enterobacter cloacae species complex as a nosocomial pathogen, little is known about the frequency of each species/genotype. Here, we describe a strain of E. hormaechei subsp.
View Article and Find Full Text PDFAn 83-year-old male patient is admitted to the central hospital in Cumana, Venezuela with severe urinary infection, history of hospitalizaions and prolonged antimicrobial treatments. A strain of Enterobacter cloacae was isolated showing resistance to multiple types of antibiotics (only sensitive to gentamicin), with phenotype of serine- and metallo-carbapenemases. Both, bla(VIM-2) and bla(KPC) genes were detected in the isolate.
View Article and Find Full Text PDFFirst report of metallo-β-lactamases producing Enterobacter spp. strains from Venezuela.
Rev Inst Med Trop Sao Paulo
April 2014
Clinical strains of Enterobacter were isolated from Cumana's Central Hospital in Venezuela, and classified as E. cloacae (21), E. aerogenes (7), E.
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