Publications by authors named "Dianne E Dewey"
J Neurophysiol
September 2005
Article Synopsis
- Inhibitory inputs to Renshaw cells are mostly found on their soma and nearby dendrites, and this study examined how this distribution impacts synaptic inhibition under varying conditions.
- Researchers created detailed models of Renshaw cells and tested the effectiveness of the inhibitory neurotransmitters glycine and GABA(A) when applied close to the cell body versus evenly across the neuron.
- The findings revealed that inhibiting inputs closer to the soma is consistently more effective, particularly under high excitation conditions, suggesting that the strategic placement of these synapses helps counter strong excitatory signals from neighboring motoneurons.
