We examined relations between positive parenting, parenting stress, and children's regulatory abilities across infancy and early childhood. First-time mothers and their infants ( = 682) were recruited prenatally. Mothers belonged to one of three potential demographic risk groups: adolescent mothers (AM), adult low-educated mothers (LEM), and adult high-educated mothers (HEM).
View Article and Find Full Text PDFData from the Early Childhood Longitudinal Study (ECLS-K; N = 6,420; 67.9% White/non-Hispanic, 15% Hispanic, 13% Black/non-Hispanic, 2% Asian, 3% Native American/Alaska Native; 25% of parents' income <$25,000, 25% = $25,001 to $45,000, 29% = $45,001 to $75,000, 20% = $75,001 or greater) were used to test structural equation models in which child externalizing or internalizing problems mediate the relation between parental physical discipline and child literacy development over time. Results show that parents' physical discipline in Kindergarten was associated with lower literacy levels in 8th grade and slower growth in literacy development from K-8.
View Article and Find Full Text PDFCalorie restriction, without malnutrition, has been shown to increase lifespan and is associated with a shift away from glycolysis toward beta-oxidation. The objective of this study was to mimic this metabolic shift using low-carbohydrate diets and to determine the influence of these diets on longevity and healthspan in mice. C57BL/6 mice were assigned to a ketogenic, low-carbohydrate, or control diet at 12 months of age and were either allowed to live their natural lifespan or tested for physiological function after 1 or 14 months of dietary intervention.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
October 2015
Calorie restriction (CR) without malnutrition extends life span in several animal models. It has been proposed that a decrease in the amount of polyunsaturated fatty acids (PUFAs), and especially n-3 fatty acids, in membrane phospholipids may contribute to life span extension with CR. Phospholipid PUFAs are sensitive to dietary fatty acid composition, and thus, the purpose of this study was to determine the influence of dietary lipids on life span in CR mice.
View Article and Find Full Text PDFThe signaling molecule p66Shc is often described as a longevity protein. This conclusion is based on a single life span study that used a small number of mice. The purpose of the present studies was to measure life span in a sufficient number of mice to determine if longevity is altered in mice with decreased Shc levels (ShcKO).
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