Publications by authors named "Dianmei Zeng"
Background: There is growing evidence suggesting that the dysregulation of circular RNAs (circRNAs) plays a significant role in various myocardial disorders, including myocardial ischemia (MI). This study aimed to explore the function of hsa_circ_0068655 (circ_0068655) in hypoxia-induced cardiomyocyte injury.
Methods: Human AC16 cardiomyocyte cells were cultured under anaerobic condition to induce an in vitro model of MI.
Article Synopsis
- The study investigates the effects of a high-salt diet on glomerulosclerosis in Dahl salt-sensitive rats, focusing on the link between endothelial-to-mesenchymal transition (EndMT) and hypertension.
- The research found that a high-salt diet significantly raised blood pressure and urinary protein levels while decreasing expressions of endothelial proteins in glomeruli, indicating glomerulosclerosis development.
- The results suggest that EndMT is crucial in the progression of glomerulosclerosis related to high-salt intake in hypertensive conditions.
Circular RNA (circRNA) is an important factor for regulating the progression of many cardiovascular diseases, including acute myocardial infarction (AMI). However, the role of circ_0124644 in AMI progression remains unclear. Hypoxia was used to induce cardiomyocytes injury.
View Article and Find Full Text PDFCircular RNAs (circRNAs) are a group of RNAs featured by a covalently closed continuous loop structure. This study aimed to uncover the function and mechanism of circ-ubiquitin specific peptidase 36 (USP36) in endothelial cells treated with oxidized low-density lipoprotein (ox-LDL). The levels of circ-USP36, microRNA-98-5p (miR-98-5p) and vascular cell adhesion molecule 1 (VCAM1) were examined by a quantitative real-time polymerase chain reaction (qRT-PCR).
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