Flagellin-modulated inflammasome pathways characterize the human alveolar macrophage response to , a lung-tropic pathogen.

Melioidosis is an emerging tropical infection caused by inhalation, inoculation, or ingestion of the flagellated, facultatively intracellular pathogen . The melioidosis case fatality rate is often high, and pneumonia, the most common presentation, doubles the risk of death. The alveolar macrophage is a sentinel pulmonary host defense cell, but the human alveolar macrophage in infection has never been studied.

The Parker B. Francis Fellowship Program: analysis of 31 years of career development support.

Rationale: The Parker B. Francis (PBF) Fellowship Program has supported more than 750 M.D.