Cornea opacity, uveitis with iris atrophy and lens damage following cosmetic high-intensity ultrasound of the eyelid: a case report.

Background: High-intensity focused ultrasound (HIFU) is a cosmetic procedure that aims to tone the skin through thermal collagen coagulation. The energy is delivered in the deep layers of the skin, and because of these characteristics, the risks of severe damage to adjacent tissue and the ocular surface may be underestimated. Previous reports have demonstrated superficial corneal opacities, cataracts, increased intraocular pressure, or ocular refractive changes in different patients following HIFU.

Eye fungal infections: a mini review.

Ocular fungal infections annually affect more than one million individuals worldwide. The management of these infections is problematic, mainly due to the limited availability of effective antifungal agents. Thus, ocular infections are increasingly recognized as important causes of morbidity and blindness, especially keratitis and endophthalmitis.

Autologous serum eye drops diluted with 0.5% methylcellulose and 0.9% saline solution: a clinical comparative study.

Purpose: This clinical study compared autologous serum eye drops diluted with 0.5% methylcellulose and 0.9% saline solution.

Conjunctival melanoma following cornea transplant from a cancer donor: A case report.

Purpose: Conjunctival melanoma is a rare ocular tumor. We report a case of ocular conjunctival melanoma during topical immunosuppression, after a corneal transplant from a donor with metastatic melanoma.

Observation: A 59-year-old white male presented with a progressive nonpigmented conjunctival lesion in his right eye.

Autologous fibrin glue versus sutures for conjunctival autograft in primary pterygium: a randomized clinical trial.

Purpose: To describe and compare the autologous fibrin glue and traditional sutures for conjunctival graft attachment in patients undergoing primary pterygium excision surgery.

Method: A randomized clinical trial included patients who underwent pterygium surgery with conjunctival autologous graft (CAG). Using randomization, a single-trained surgeon performed graft fixation with autologous glue or sutures.

Clinical and molecular diagnosis of Acanthamoeba keratitis in contact lens wearers in southern Brazil reveals the presence of an endosymbiont.

Acanthamoeba keratitis (AK) is an infection that is mostly observed in contact lens wearers. It is often misdiagnosed causing delays in the administration of the correct treatment. The aim of this study was to report the outcome of clinical and molecular diagnosis of AK cases during the summer of 2019 in the southern region of Brazil.

The influence of luminous intensity on the eyelid aperture and measurement of the margin reflex distance.

Purpose: To evaluate whether the flashlight feature of smartphones can be used to replace the traditional flashlight for measuring MRD and investigate the relation between increasing light intensities and MRD measurements.

Methods: A prospective clinical study was conducted with 40 individuals from Hospital de Clínicas de Porto Alegre. Outcome measures: MRD1, MRD2, and palpebral fissure height (PFH) were analyzed by photographic record using different intensity light sources.

Keratoconus progression after intrastromal corneal ring segment implantation according to age: 5-year follow-up cohort study.

Background/aims: Intrastromal corneal ring segments (ICRS) have been found to be useful in correcting keratoconus by decreasing irregular astigmatism, thereby potentially improving visual acuity. However, its long-term effects in keratoconus progression are not completely understood, mainly concerning the effects of age on ICRS implantation results. This study aimed to evaluate long-term effects of ICRS implantation according to age at implantation.

Long-term results of accelerated and conventional corneal cross-linking.

Purpose: The aim of this study is to compare the long-term follow-up outcomes of traditional and accelerated corneal cross-linking (CXL) for keratoconus.

Methods: This retrospective comparative cohort study included patients with keratoconus who underwent corneal cross-linking (CXL) between August 2008 and December 2016. Patients treated before August 2013 underwent the traditional Dresden protocol, and those treated subsequently received the accelerated protocol, i.

Recommendations for the management of MPS IVA: systematic evidence- and consensus-based guidance.

Introduction: Mucopolysaccharidosis (MPS) IVA or Morquio A syndrome is an autosomal recessive lysosomal storage disorder (LSD) caused by deficiency of the N-acetylgalactosamine-6-sulfatase (GALNS) enzyme, which impairs lysosomal degradation of keratan sulphate and chondroitin-6-sulphate. The multiple clinical manifestations of MPS IVA present numerous challenges for management and necessitate the need for individualised treatment. Although treatment guidelines are available, the methodology used to develop this guidance has come under increased scrutiny.

Recommendations for the management of MPS VI: systematic evidence- and consensus-based guidance.

Introduction: Mucopolysaccharidosis (MPS) VI or Maroteaux-Lamy syndrome (253200) is an autosomal recessive lysosomal storage disorder caused by deficiency in N-acetylgalactosamine-4-sulfatase (arylsulfatase B). The heterogeneity and progressive nature of MPS VI necessitates a multidisciplinary team approach and there is a need for robust guidance to achieve optimal management. This programme was convened to develop evidence-based, expert-agreed recommendations for the general principles of management, routine monitoring requirements and the use of medical and surgical interventions in patients with MPS VI.

Posterior keratoconus and iris atrophy: a fortuitous association?

The authors describe an unusual association between posterior keratoconus and iris atrophy, confirmed by a complete ocular evaluation, scheimpflug imaging and pachymetric curve. A hypothesis for concomitant findings is discussed.

Classic homocystinuria and keratoconus: a case report.

Homocystinuria is one of a group of genetic disorders called inborn errors of metabolism. It is characterized by a deficiency of the enzyme that converts homocysteine to cystathionine. Keratoconus is an ophthalmologic condition characterized by thinning of the corneal stroma, which causes the cornea to assume a conical shape.

Effects of sub-Tenon's triamcinolone injections in patients with uveitis.

Purpose: To evaluate the response to sub-Tenon's triamcinolone injection in patients with uveitis.

Methods: We studied 28 eyes with macular edema associated with controlled uveitis. We administered sub-Tenon's injection of triamcinolone and followed the patients for 180 days to analyze the positive effects (improvement of macular edema and visual acuity) and monitor the possible adverse effects.

Virulent T4 Acanthamoeba causing keratitis in a patient after swimming while wearing contact lenses in Southern Brazil.

Several strains of free-living amoebae belonging to the genus Acanthamoeba can cause a painful sight-threatening disease of the cornea known as Acanthamoeba keratitis (AK). The numbers of AK cases keep rising worldwide mainly due to an increase in contact lens wearers and lack of hygiene in the maintenance of contact lenses and their cases. We report a case of AK in a healthy young woman admitted to the Hospital de Clinicas in Porto Alegre, southern Brazil.

Acanthamoeba keratitis in Porto Alegre (southern Brazil): 28 cases and risk factors.

The increasing use of contact lenses worldwide has led to an increase in cases of Acanthamoeba keratitis, which are often associated with inappropriate cleaning of contact lenses and lens cases. This study aimed to retrospectively review 28 cases of Acanthamoeba keratitis in Porto Alegre (southern Brazil) and identify the risk factors and clinical outcomes of affected patients. Most patients had higher education (66.

Optical coherence tomography image in gelatinous drop-like corneal dystrophy: case report.

Gelatinous drop-like corneal dystrophy is a rare disorder with few cases described in the present literature. The following report will show how difficult it is to diagnose this disease in early stages. Modern image exams, such as optical coherence tomography helps to diagnose and can be crucial to establish the best treatment.

Visual Dysfunction of Type I and VI Mucopolysaccharidosis Patients Evaluated with Visual Evoked Cortical Potential.

Purpose: To evaluate the visual system of patients suffering from type I or VI mucopolysaccharidosis (MPS) by recording the visual evoked cortical potential (VECP).

Methods: Two patients with MPS VI and 2 patients with MPS I were tested before and after enzyme replacement therapy (ERT). A control group of 20 subjects was tested for statistical comparison.

Fovea center detection based on the retina anatomy and mathematical morphology.

In this work, we present a new fovea center detection method for color eye fundus images. This method is based on known anatomical constraints on the relative locations of retina structures, and mathematical morphology. The detection of this anatomical feature is a prerequisite for the computer aided diagnosis of several retinal diseases, such as Diabetic Macular Edema.

Segmentation of the optic disk in color eye fundus images using an adaptive morphological approach.

The identification of some important retinal anatomical regions is a prerequisite for the computer aided diagnosis of several retinal diseases. In this paper, we propose a new adaptive method for the automatic segmentation of the optic disk in digital color fundus images, using mathematical morphology. The proposed method has been designed to be robust under varying illumination and image acquisition conditions, common in eye fundus imaging.

A coarse-to-fine strategy for automatically detecting exudates in color eye fundus images.

The detection of exudates is a prerequisite for detecting and grading severe retinal lesions, like the diabetic macular edema. In this work, we present a new method based on mathematical morphology for detecting exudates in color eye fundus images. A preliminary evaluation of the proposed method performance on a known public database, namely DIARETDB1, indicates that it can achieve an average sensitivity of 70.

[Use of fibrin glue in ocular surgery].

Purpose: To evaluate the use of fibrin glue and its complications in different ophthalmic surgeries.

Methods: A retrospective and non-comparative case series study. 161 eyes were evaluated.

Femoral and acetabular revision using impacted nondemineralized freeze-dried bone allografts.

Background: Favorable results have been obtained by the use of deep-frozen bone allografts in total hip arthroplasty. However, owing to the shortage of deep-frozen allografts and the risk of infectious disease, other materials have been studied, such as sterile nondemineralized freeze-dried allografts. The aim of this study was to describe midterm clinical outcomes and radiographic bone incorporation of human freeze-dried bone grafts in 42 revision total hip arthroplasty procedures using cancellous impacted bone grafting.

A morphological approach for the fovea location in color fundus images.

This paper presents a novel method for the detection of the fovea center in color fundus images. The method was evaluated using a set of 89 images from the DIARETDB1 project, which contains images presenting normal and pathological situations. Using the Mean Absolute Distance (MAD) as a metric, we report 7.