Publications by authors named "Diane Rivet-Danon"

Background: Transgender men face reproductive challenges due to the potential impact on fertility of gender-affirming hormone therapy (GAHT) and surgical interventions. Testosterone therapy during "female to male" transition leads to anovulation and amenorrhea. Although these effects are typically reversible upon stopping treatment, the long-term effects of androgens on future fertility and health of potential children remain poorly known.

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  • * A study analyzed data from 117 women in same-sex couples and 75 women in heterosexual couples seeking MAR, comparing their profiles and ART outcomes from October 2021 to October 2022.
  • * Results showed no significant differences in age, ovarian reserve, or pregnancy outcomes between the two groups, indicating that women in same-sex couples have similar profiles and ART experiences to those in heterosexual couples following the law's implementation.
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Azoospermia, defined as the absence of sperm in the semen, is found in 10-15 % of infertile patients. Two-thirds of these cases are caused by impaired spermatogenesis, known as non-obstructive azoospermia (NOA). In this context, surgical sperm extraction using testicular sperm extraction (TESE) is the best option and can be offered to patients as part of fertility preservation, or to benefit from in vitro fertilization.

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  • The study explores how human embryos undergo compaction, which is crucial for their development, revealing that defects in adhesion lead to compaction failure.
  • Researchers used micropipette aspiration to investigate cell surface tensions during compaction, finding that increased tension at the cell-medium interface is critical for this process, mirroring findings in mouse embryos but showing less efficiency in humans.
  • The research highlights the distinct roles of cell contractility and cell-cell adhesion in embryo compaction, showing that contractility is essential for generating the forces required for the initial morphogenetic movements in human development.
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  • In France, a law about helping people have babies through different methods, called Medically Assisted Reproduction (MAR), has changed a lot since 1994, with a big update in 2021.
  • The new law allows more people, like couples of women and single women, to get sperm donations and lets anyone store their eggs or sperm if they are the right age.
  • It also gives people born from donated eggs or sperm the chance to find out some information about their donor when they turn 18, which has led to more requests for this help in fertility centers.
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Background: Testicular sperm extraction (TESE) is an essential therapeutic tool for the management of male infertility. However, it is an invasive procedure with a success rate up to 50%. To date, no model based on clinical and laboratory parameters is sufficiently powerful to accurately predict the success of sperm retrieval in TESE.

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Objectives: Current methods for cryptococcal antigen detection have some limitations. This study aimed at evaluating a lateral flow assay (LFA) for the diagnosis of cryptococcosis in a French University medical center.

Methods: A retrospective study was performed on samples collected from patients with a definitive diagnosis of cryptococcosis (group I 66 samples; 28 patients) or with non-Cryptococcus invasive fungal infection (group II 18 samples; 17 patients).

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