Publications by authors named "Diane Osinski"
Introduction: Avoiding coronavirus disease 2019 (COVID-19) work-related infection in frontline healthcare workers is a major challenge. A massive training program was launched in our university hospital for anesthesia/intensive care unit and operating room staff, aiming at upskilling 2249 healthcare workers for COVID-19 patients' management. We hypothesized that such a massive training was feasible in a 2-week time frame and efficient in avoiding sick leaves.
View Article and Find Full Text PDFBackground: The typical sign of intracranial hypotension (IH) is postural headache. However, IH can be associated with a large diversity of clinical or radiological signs leading to difficult diagnosis especially in case of coma. The association of cerebral venous thrombosis (CVT) and subdural hemorrhage is rare but should suggest the diagnosis of IH.
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- - The study investigates the effectiveness of a revised computed tomography angiography (CTA) score that includes superior petrosal veins (SPVs) for confirming brain death (BD), comparing it to the established 4-point score.
- - The research analyzed 69 adult patients who met clinical brain death criteria, finding that the new "Toulouse score" showed a positive predictive value of 100% and the lowest misclassification rate compared to the 4-point score.
- - The results suggest that incorporating SPVs and middle cerebral arteries into the score aids in accurately confirming brain death, maintaining similar sensitivity to the traditional 4-point score, especially in cases where craniectomy has occurred.
Study Objective: To assess incidence and predicting factors of awake craniotomy complications.
Design: Retrospective cohort study.
Setting: Operating room and Post Anesthesia Care unit.
Background: In several countries, a computed tomography angiography (CTA) is used to confirm brain death (BD). A six‑hour interval is recommended between clinical diagnosis and CTA acquisition despite the lack of strong evidence to support this interval. The aim of this study was to determine the optimal timing for CTA in the confirmation of BD.
View Article and Find Full Text PDFCentral congenital hypoventilation syndrome is a neuro-respiratory disease characterized by the dysfunction of the CO2/H(+) chemosensitive neurons of the retrotrapezoid nucleus/parafacial respiratory group. A recovery of CO2/H(+) chemosensitivity has been observed in some central congenital hypoventilation syndrome patients coincidental with contraceptive treatment by a potent progestin, desogestrel (Straus et al., 2010).
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- The study aimed to determine if emergency platelet transfusions can restore platelet function in patients taking antiplatelet medications like aspirin and clopidogrel.
- A total of 25 patients were analyzed, revealing that while transfusions significantly decreased clopidogrel inhibition levels, patients remained responsive to the drug; in contrast, aspirin users showed improved platelet function after transfusion.
- The conclusion suggests that while platelet transfusions effectively restore function in aspirin users, they do not fully restore function for those on clopidogrel.