Introduction: Cases of conjoined twins occur so rarely that it is important to learn as much as possible from each case.
Case Presentation: We present a case of 9-hour-old, female, Nigerian dicephalus parapagus conjoined twins discordant for anencephaly diagnosed only after the birth of the twins. The anencephalic twin was stillborn while the normal one died within 9 hours of birth from cardiopulmonary failure.