Effect of Preoperative Oral Cannabidiol-Rich Cannabis Extract on Anxiety and Postoperative Pain after Endodontic Treatment: A Double-Blind Randomized Clinical Trial.

Introduction: The aim of the present study was to evaluate the effectiveness of cannabidiol (CBD)-rich Cannabis extract in reducing anxiety and postoperative pain in patients submitted to endodontic treatment.

Methods: The study was carried out after approval by the Research Ethics Committee (Registration No. 5.

Treatment of Invasive Cervical Resorption in a Central Incisor by Intentional Replantation: A Case Report.

Invasive cervical resorption (ICR) is an aggressive pathological condition that can affect any permanent tooth. This process is characterized by replacement of the tooth structure with granulomatous fibrovascular or fibro-osseous tissue. Despite its asymptomatic nature, ICR can lead to tooth loss.

Proteins Associated with Persistent Apical Periodontitis: A Scoping Review.

This scoping review aimed to assess immunohistochemical markers associated with the physiopathogenesis of Persistent Apical Periodontitis. The protocol was adapted from the Joanna Briggs Institute Reviewer's Manual (2017) and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for Scoping Reviews. A total of 239 articles were considered potentially eligible, and their full texts read by two reviewers.

Pulp Canal Obliteration Following Traumatic Dental Injury in an Upper Lateral Incisor: A Case Report with 3-year Follow-up.

Endodontic management of teeth afflicted with pulp canal obliteration faces a challenge due to the heightened risk of complications including excessive wear, perforation, and suboptimal chemomechanical preparation. This report aims to elucidate the clinical endodontic strategy employed in addressing pulp canal obliteration after a history of dental trauma and an associated periradicular lesion in an upper lateral incisor. A patient visited the dental emergency department with symptoms of apical swelling, acute persistent pain, and discoloration of tooth 22.

Clinicopathological characteristics of odontogenic carcinosarcoma: A systematic review.

Background: The aim of the present systematic review was to summarize evidence on odontogenic carcinosarcoma, analyzing clinical, epidemiological, imaging, histopathological, immunohistochemical, therapeutic, and prognostic features of this tumor.

Materials And Methods: This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Searches were performed in the Ovid MEDLINE (Wolters Kluwer), PubMed (National Library of Medicine), Web of Science (Thomson Reuters), Scopus (Elsevier), and LILACS (Latin American and Caribbean Center on Health Sciences Information) databases, without publication date or language restrictions.

Endodontic and Surgical Management of an Invasive Cervical Resorption in a Maxillary Central Incisor: A Case Report.

The current study aims to report a case of invasive cervical resorption in a maxillary left central incisor with a history of dental trauma. After thorough clinical and tomographic evaluations, cervical cavitation, an irregularity in the gingival contour and crown discoloration were observed. Furthermore, presence of an extensive and well-defined area of invasive cervical resorption with pulp communication was discovered.

Cyclic Fatigue Resistance of Blue Heat-Treated Instruments at Different Temperatures.

The main aim is to evaluate the cyclic fatigue resistance of blue heat-treated instruments with different kinematics. Twenty-four endodontic instruments of the same brand were used for each of three experimental groups: VB (Vortex Blue 40/0.04), RB (RECIPROC Blue 40/0.

Influence of occlusal reduction on pain after endodontic treatment: a systematic review and meta-analysis.

The purpose of this systematic review was to analyze the influence of occlusal reduction on the postoperative pain levels after endodontic treatment (instrumentation and obturation of the root canal system). This review followed the PRISMA statement and was registered at PROSPERO (CRD42018107918). Two independent reviewers searched the Lilacs, Cochrane Library, PubMed (Medline), Web of Science, Scopus, Scielo, and ScienceDirect for articles published until April 2021.

Photobiomodulation Therapy in the Proliferation and Differentiation of Human Umbilical Cord Mesenchymal Stem Cells: An Study.

Since photobiomodulation therapy (PBMT) favors mesenchymal stem cell (MSC) preconditioning before MSC transplantation, increasing the proliferation of these cells without molecular injuries by conserving their characteristics, in the present study we analyzed the effect of PBMT on the proliferation and osteogenic differentiation of human umbilical cord mesenchymal stem cells (hUCMSCs). Irradiation with an InGaAIP Laser (660 nm, 10 mW, 2.5 J/cm , 0.

Tooth autotransplantation using an interdisciplinary approach to rehabilitation in a young patient: Case report with 7-year follow-up.

This case report demonstrates the possibility of functional and aesthetic rehabilitation using an interdisciplinary approach in a child following avulsion of a tooth. Autotransplantation after the development of calcific metamorphosis of the pulp and acute apical periodontitis provided satisfactory repair after root canal treatment. A 7-year-old white boy avulsed the right maxillary central incisor (tooth 11).

Influence of Temperature on the Cyclic Fatigue of Nickel-Titanium Instruments with Different Heat Treatments on Severely Curved Canals.

Aim: This study aims to investigate the influence of temperatures of 20 °C and 37 °C on the resistance to cyclic fatigue of NiTi instruments with different heat treatments, as tested in severely curved simulated canals.

Materials And Methods: Seventy-two instruments were distributed according to the temperature used (20 °C and 37 °C): XP-endo Shaper (30/0.01), ProDesign Logic (30/0.

Analysis of Aloe vera cytotoxicity and genotoxicity associated with endodontic medication and laser photobiomodulation.

This study aims to evaluate, in vitro, the effect of Aloe vera associated with endodontic medication, with or without laser photobiomodulation (FTL) irradiation in FP6 human pulp fibroblasts. The materials were divided into eight groups: CTR - control; CL - FTL alone; AA - Aloe vera with distilled water; AL - Aloe vera with distilled water and FTL; HA - calcium hydroxide P.A.

The Promising Applications of Stem Cells in the Oral Region: Literature Review.

Introduction: For a long time researchers have tried to find out a way to grow tissues back to the human body in order to solve transplantation problems by offering the unique opportunity to have their organs back, working properly, in search of life dignity.

Literature Review: Stem cells seem to be present in many other tissues than researchers had once thought; and in some specific sites they can be easily collected, without the need of expensive interventions. The oral cavity is one of these regions where their collection can be accomplished, with plenty of accessible sites enriched with these precious cells.

Efficacy of ProTaper NEXT Compared with Reciproc in Removing Obturation Material from Severely Curved Root Canals: A Micro-Computed Tomography Study.

Introduction: The aim of this study was to compare the remaining root canal obturation, volume of dentin removed, and apical transportation after retreatment of severely curved root canals by using Reciproc (REC) or ProTaper NEXT (PTN) systems.

Methods: Twenty-eight mesial canals of mandibular molars were instrumented and then obturated with gutta-percha and sealer and allocated into 2 balanced groups (n = 14), the REC group (R25 file) and the PTN group (X3 and X2 files). Micro-computed tomography analysis was performed to assess the percentage of residual obturation material, the amount of dentin removed, and apical transportation.

Detection of vertical root fractures in endodontically treated teeth in the absence and in the presence of metal post by cone-beam computed tomography.

Background: Aim of this study was to investigate the influence of gutta-percha and metallic posts on the efficiency of Cone Beam Computed Tomography (CBCT) in diagnosing Vertical Root Fracture (VRF).

Methods: Forty-eight teeth were divided into 3 experimental and 3 control groups. The teeth of the first experimental group and the first control group received neither gutta-percha nor metal posts.

IS GUTTACORE MORE EASILY REMOVED FROM THE ROOT CANAL THAN THERMAFIL? AN EX-VIVO STUDY.

GuttaCore is a new cross-linked gutta-percha carrier. Its handling time and ease of removal were compared with those of a plastic carrier (Thermafil) and the continuous wave of condensation technique (control). Forty-five maxillary central incisors were randomly divided 3 groups according to filling technique and retreatment was carried out in all samples with NiTi rotary files, hand files and ultrasonic inserts.

Filling lateral canals: influence of calcium hydroxide paste as a root canal dressing.

Context: The use of intracanal medication aims to provide antimicrobial activity in the root canal system, leading to a more satisfactory condition for root canal obturation. However, it is important to evaluate whether such medication would affect the sealing-off from the main root canal of ramifications such as lateral canals.

Aim: Evaluate the influence of calcium hydroxide [Ca(OH)2] paste on the filling of lateral canals.

Short-term analysis of human dental pulps after direct capping with portland cement.

This study evaluated the short-term response of human pulp tissue when directly capped with Portland cement. In this series of cases, twenty human third molars that were scheduled for extraction were used. After cavity preparation, pulp exposure was achieved and Portland cement pulp capping was performed.

In vitro comparative study of manual and mechanical rotary instrumentation of root canals using computed tomography.

This in vitro study compared, using computed tomography (CT), the amount of dentin removed from root canal walls by manual and mechanical rotary instrumentation techniques. Forty mandibular incisors with dental crown and a single canal were selected. The teeth were randomly assigned to two groups, according to the technique used for root canal preparation: Group I - manual instrumentation with stainless steel files; Group II - mechanical instrumentation with RaCe rotary nickel-titanium instruments.

The accuracy of root canal measurements using the Mini Apex Locator and Root ZX-II: an evaluation in vitro.

Objective: The aim of this in vitro study was to compare the capacity of the Root ZX-II and Mini Apex Locator, electronic apex locators (EALS), to prevent overestimated working length.

Study Design: Forty extracted human teeth were used for the study. The cervical portion of each canal was flared using Gates Glidden drills and the teeth were embedded in an alginate model.

Histologic evaluation of pulpotomy performed with ethyl-cyanoacrylate and calcium hydroxide.

The aim of this study was to evaluate histological aspects of the pulp-dentin complex of dogs submitted to pulpotomy and capped with ethyl-cyanoacrylate and calcium hydroxide. Thirty dog teeth were divided into 2 groups of 15 as follows: Group 1 - ethyl-cyanoacrylate; Group 2 - calcium hydroxide. The pulpotomies were carried out following all of the treatment precautions recommended for dogs.

The ability of two apex locators to locate the apical foramen: an in vitro study.

The objective of this study was to compare the accuracy of the Root-ZX and Novapex electronic apex locators (EALs) in locating the apical foramen. Forty extracted human teeth were used. The coronal portion of each canal was flared using Gates Glidden drill.