Publications by authors named "Diana Roda"
Objectives: The aim of this study is to determine the prevalence and characteristics of fractures in young infants attended at the pediatric emergency department (PED).
Methods: This is a retrospective study for 2 years (2011-2012) of children younger than 12 months attended with a fracture at the PED. Age, sex, site and type of fracture, mechanism of injury, time interval before seeking medical attention, and management were analyzed.
Article Synopsis
- - Human parechovirus (HPeV) is a recently identified virus linked to serious conditions like fever of unknown origin and meningitis in young infants; this study aimed to explore its epidemiology and clinical features.
- - Over three years, a study in 12 hospitals in Spain found that 5.52% of 850 specimens tested positive for HPeV, predominantly HPeV-3, with most cases occurring in neonates, highlighting symptoms such as fever, irritability, and gastrointestinal issues.
- - The study concluded that HPeV infections primarily occur in the spring and summer months, with a significant number of infants experiencing severe symptoms; it suggested that enhanced molecular diagnostic methods could improve patient care.
Cholecystitis and nephrotic syndrome complicating Epstein-Barr virus primary infection.
Paediatr Int Child Health
February 2017
Epstein-Barr virus (EBV) infection results in a spectrum of clinical manifestations. The host immune response to EBV plays a key role in the extent and degree of clinical features, which in children under 4 years of age are usually mild, non-specific and self-limiting. A 2-year-old boy in whom no known immune disorder could be found presented with acute acalculous cholecystitis, renal dysfunction with massive proteinuria, ascites, pleural effusion, minimal peripheral oedema and a severe systemic inflammatory response.
View Article and Find Full Text PDFIsoniazid exposure causes dose-dependent pyridoxine deficiency. Recently, the recommended dosage of isoniazid in children was increased from 5 (4-6) to 10 (10-15) mg/kg/day. We aimed to analyze longitudinally pyridoxine levels in a cohort of previously healthy children and adolescents treated with isoniazid.
View Article and Find Full Text PDFUnlabelled: Enterovirus (EV) infection is common in infants, but the information with regard to the molecular epidemiology and the associations between types and clinical variables is very scarce. This study includes 195 children <3 months old with fever, attended from March 2010 to December 2012 in an emergency department of a tertiary paediatric hospital in whom EV infection was confirmed by real-time PCR in blood and/or cerebrospinal fluid. Clinical and epidemiological data was prospectively collected.
View Article and Find Full Text PDFArticle Synopsis
- Human parechoviruses (HPeV) are important viral pathogens in infants, particularly those under 1 month old, and this study aimed to assess their prevalence and compare clinical features with enterovirus (EV) infections.
- In a study of 84 infants, 11% tested positive for HPeV, predominantly HPeV-3, with common diagnoses including fever without source and clinical sepsis, while the presence of pleocytosis and meningitis was significantly more frequent in EV cases.
- The findings suggest that HPeV-3, though less prevalent than EV, is relevant in young infants, and screening for HPeV is important to accurately diagnose and manage these infections, potentially reducing unnecessary treatments and hospital
Norovirus-associated encephalitis in a previously healthy 2-year-old girl.
Pediatr Infect Dis J
February 2015
We describe the case of 2-year-old girl with encephalitis associated with norovirus infection. The viral genome was detected in cerebrospinal fluid and stool by reverse transcription polymerase chain reaction. This is the first time in Spain and the second worldwide that the genome of norovirus from the stool sample and 2 cerebrospinal fluid samples were genetically characterized and matched.
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