Publications by authors named "Diana Man Ka Chan"
Article Synopsis
- The study investigated whether oral progestogen could reduce miscarriage rates in women experiencing threatened miscarriage during their first trimester compared to a placebo.
- The results indicated that there was no significant difference in miscarriage rates before 20 weeks, with 12.8% in the progestogen group and 14.3% in the placebo group.
- Overall, the use of oral progestogen did not improve outcomes in these cases, aligning with previous findings regarding vaginal progestogens.
Background: Miscarriage is a common complication of pregnancy occurring in 15-20 % of all clinically recognized pregnancies. Currently, there is still no good scientific evidence to support the routine use of progestogens for the treatment of threatened miscarriage because the existing studies were not large enough to show a significant difference and some of them were not randomized or double-blind.
Methods: This is a double-blind, randomized controlled trial.