Podoplanin is a better immunohistochemical marker for sarcomatoid mesothelioma than calretinin.

Immunohistochemistry using a broad panel of markers is an invaluable tool for diagnosing sarcomatoid mesothelioma. Membranous podoplanin staining has been proposed as a specific and sensitive marker to distinguish epithelioid mesothelioma from adenocarcinoma. We found that cytoplasmic podoplanin staining was present in sarcomatoid mesotheliomas, and wanted to explore the reproducibility and specificity of this staining pattern.

Multiple hibernomas in a 1-month-old female infant.

Hibernoma is a rare benign soft tissue tumor composed of remnants of fetal brown fat. It has only rarely been reported in the literature in patients ranging in age from 2 to 75 years. We present a case of multiple hibernomas occurring in a 1-month-old infant.