Publications by authors named "Diana Laura Perez-Osornio"
Behav Brain Res
February 2025
Article Synopsis
- Dendritic spine pathology involves changes in the structure and density of dendritic spines in neurons, which are important for understanding schizophrenia's neurobiological aspects, particularly in the corticolimbic system.
- A model using neonatal ventral hippocampus lesions in rats mirrors schizophrenia symptoms and related dendritic spine changes; atypical antipsychotic drugs like risperidone and olanzapine can help alleviate these issues.
- The research shows that these drugs increase dendritic spine density and the beneficial mushroom spine type while reducing less favorable stubby spines, highlighting the crucial role of neuroplasticity in the temporal lobe for schizophrenia treatments.
