Tick Tock-A Matter of Time: Two Cases of Babesia Acquired in Urban Newark, NJ.

Babesiosis is a parasitic tick-borne infectious disease that is well elucidated in medical literature and known to be endemic to the Midwest and northeast United States. However, like other infectious diseases, its epidemiology is subject to change. This case report documents two cases with clinical presentations that deviate from what is expected in typical cases of Babesiosis.

Endocarditis Presenting with Brain Abscesses and Temporal Vision Deficits.

is a coagulase-negative staphylococcal bacterium (CoNS) that colonizes the skin. While infectious endocarditis (IE) caused by is rare, it is noteworthy because it has been associated with an aggressive clinical course. In this report, we present a case of culture-negative IE complicated by brain abscesses, vision deficits, and progressive heart failure that ultimately required mitral valve replacement.

A case of cryptococcoma in an immunocompetent man with polysubstance use.

Cryptococcus most commonly affects the pulmonary and central nervous systems in patients who are immunocompromised. It is most likely to present as meningitis. However, it can affect immunocompetent patients in the cerebral parenchyma.

Progression of chronic rhinosinusitis to invasive cerebro-orbital aspergillosis following steroid treatment: A case of induced immunosuppression.

Invasive aspergillosis is a classic fungal infection of immunocompromised hosts which rarely manifests in immunocompetent patients. In this report, we present a case of invasive aspergillosis which resulted from induced immunosuppression through corticosteroid treatment of chronic rhinosinusitis. Further investigation is necessary into the epidemiology of mixed fungal rhinosinusitis and providers should be wary of invasive disease in those receiving chronic steroids.

Clinical Impact of Skin and Soft Tissue Infections.

The pathogenic bacterium is the most common pathogen isolated in skin-and-soft-tissue infections (SSTIs) in the United States. Most SSTIs are caused by the epidemic clone USA300 in the USA. These infections can be serious; in 2019, SSTIs with were associated with an all-cause, age-standardized mortality rate of 0.

sepsis causing purpura fulminans in a 50-year-old man with chronic opioid use.

We present a case of polymicrobial sepsis with spp. complicated by purpura fulminans following a dog-bite in a 50-year-old-man with an extensive history of opioid use disorder. Generally, severe cases are thought to occur in patients with underlying immune deficiencies.

An unusual case of Lemierre syndrome - One pathogen or two?

Lemierre syndrome, or septic thrombophlebitis of the internal jugular vein, is a rare disease that affects healthy young adults following an episode of pharyngitis or other upper respiratory disease. It most commonly involves the anaerobe , a component of normal oral flora. In this report, we present an unusual case of polymicrobial Lemierre syndrome involving both and Group C streptococcus following an episode of pharyngitis and streptococcal toxic shock syndrome.

Marked Sinus Bradycardia Associated With Remdesivir in COVID-19: A Case and Literature Review.

Remdesivir has seen extensive use during the coronavirus disease-2019 pandemic given its clinically proven efficacy against severe acute respiratory syndrome coronavirus type 2. There has been little cited regarding adverse effects. Here we present the case of a patient with marked sinus bradycardia that began acutely on initiation of remdesivir and resolved almost immediately on cessation of the drug.

Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19.

Importance: Therapies that improve survival in critically ill patients with coronavirus disease 2019 (COVID-19) are needed. Tocilizumab, a monoclonal antibody against the interleukin 6 receptor, may counteract the inflammatory cytokine release syndrome in patients with severe COVID-19 illness.

Objective: To test whether tocilizumab decreases mortality in this population.

Prevalence of GB virus type C in urban Americans infected with human immunodeficiency virus type 1.

GBV-C virus infection has been linked to improved clinical outcome in HIV-1 co-infected individuals. The epidemiology of GBV-C has, thus far, been limited to the gay male, HIV+ population. Here we describe the prevalence of antibodies against GBV-C envelope glycoprotein E2 and GBV-C viremia in an HIV+ inner city population.

[Psychotropic coadjuvants in pain treatment].

Conventionally, analgesic treatment is accomplished by three principal drug groups, like nonsteroidal anti-inflammatory drugs, opioids, and local anesthetics, through different administration routes and modalities. Currently, those analgesics are complemented with coadjuvant and coanalgesic drugs, particularly the psychotropic drugs, specially in somatic or visceral pain, inflammatory, neurophatic or oncologic types. Recently, best understanding of pathophysiological scopes relatives to inflammatory processes and neural damage in pain, makes possible an optimum and rational employment of those drugs.