The impact of dietary therapy on clinical and biologic parameters of pediatric patients with eosinophilic esophagitis.

Background: Eosinophilic esophagitis (EoE) is a clinicopathologic disease that presents with a massive infiltration of the esophagus by eosinophils triggered by food antigen(s).

Objective: To determine the impact of dietary therapy on nutritional parameters in patients who present with EoE.

Methods: A convenience retrospective study analyzed patients with EoE after a 2-month dietary therapy (6-food elimination diet, avoidance of the 6 most common allergenic foods, plus avoidance of those eliciting positive skin testing, plus amino-acid formula as replacement for dairy products).

Serum immunoglobulin free light chain levels are higher in girls than boys during eosinophilic oesophagitis.

Aim: Eosinophilic oesophagitis (EO) is an emerging worldwide disease, closely associated with male gender and allergic disorders. This study investigated the distribution of allergy markers in a cohort of children with EO.

Methods: We analysed allergy markers in 91 children (62 males and 29 females) with EO and a control group of 45 age-matched children who had non-EO gastrointestinal allergic symptoms.