Publications by authors named "Dian-Chen Wu"
Article Synopsis
- Crotoxin (Cro), a neurotoxin from the Crotalus durissus terrificus snake, was found to reduce pain-related neuron activity in a rat study, indicating potential analgesic effects.
- The study used microelectrodes to measure the effects of different doses of Cro on neuronal discharge in the thalamic parafascicular nucleus, revealing a significant decrease in discharge frequency and duration with higher doses.
- The pain-inhibiting effects of Cro were diminished when the serotonergic system was disrupted, suggesting that its analgesic properties are at least partly mediated through serotonin pathways.
