A new device to simplify flexible endoscopic treatment of Zenker's diverticulum.

Background: Endoscopic treatment of a Zenker's diverticulum (ZD) is challenged by maintaining a stable position and visual field. An oblique transparent cap and an overtube have been used with success. The porcine hypopharyngeal pouch is similar to a ZD.

An animal training model for endoscopic treatment of Zenker's diverticulum.

Background: Zenker's diverticulum (ZD) is an uncommon disease, which is typically treated surgically. The alternative to surgery is a diverticulotomy, performed endoscopically. Given the rarity of this condition, it is not possible to obtain training.

Tissue anchors for transmural gut-wall apposition.

Background: With the development of NOTES (natural orifice transluminal endoscopic surgery) and efforts to advance gastric reduction surgery, alternatives for robust tissue apposition apart from suturing and current mucosal clipping devices may be valuable.

Objectives: We attempted to identify functional tissue anchors that could be deployed endoscopically, with the potential to provide transmural tissue apposition.

Design: Short-term animal-survival study.