Protective effects of trans-2, 4-dimethoxystibene on cognitive, impairments induced by Abeta(25-35) in, hypercholesterolemic rats.

Trans-2, 4-dimethoxystibene (S3) is a synthetic stilbenes. In the present study, S3 was investigated to assess its neuroprotective effect against the toxicity induced by Abeta(25-35) in hypercholesterolemic rats. Rats were fed with hypercholesterolemic chow for six weeks, and then received a single intracerebroventricular (i.

Effects of trans-2,4-dimethoxystibene against the neurotoxicity induced by Abeta(25-35) both in vitro and in vivo.

Trans-2,4-dimethoxystibene (S(3)) is a synthetic stilbene. In this study, S(3) was investigated in terms of its neuroprotective effect against the toxicity induced by beta-amyloid(25-35) (Abeta(25-35)) both in vitro and in vivo. Protection by S(3) was studied at the in vivo level using a model of intracerebroventricular (i.

Protective effect of stilbenes containing extract-fraction from Cajanus cajan L. on Abeta(25-35)-induced cognitive deficits in mice.

Cajanus cajan (L.) is a traditional Chinese herb medicine which contains a lot of potential active components. In the present study, we identified the effects of the stilbenes containing extract-fraction from C.

Immunosuppressive effects of new cyclolanostane triterpene diglycosides from the aerial part of Cimicifuga foetida.

Two new cyclolanostane diglycosides, cimifoetiside A (1) and cimifoetiside B (2), were isolated from an 80% ethanolic extract of the aerial part of Cimicifuga foetida L. (Ranuculaceae). Using spectral data and chemical analysis, the structures of 1 and 2 were identified as (23R, 24S) cimicigenol 3-O-beta-D-glucopyranosyl-(1''-->3')-beta-D-xylopyranoside and (23R, 24S) cimicigenol 3-O-beta-D-glucopyranosyl-(1''-->2')-beta-D-xylopyranoside, respectively.

[Hypocholesterolemic effect of stilbene extract from Cajanus cajan L. on serum and hepatic lipid in diet-induced hyperlipidemic mice].

Cajanus cajan L. is a natural plant, which contains a lot of potential active components. In the present study, we identified the effects of the stilbene extract from Cajanus cajan L.

Hypocholesterolemic effect of stilbenes containing extract-fraction from Cajanus cajan L. on diet-induced hypercholesterolemia in mice.

Cajanus cajan (L) is a natural plant which contains a lot of potential active components. In the present study, we identified the effects of the stilbenes containing extract-fraction from Cajanus cajan L (sECC) on diet-induced (for 4 weeks) hypercholesterolemia in Kunming mice. All experimental mice were divided into 5 groups: control group, model group, sECC-treated with 200 or 100 mg/kg/day, and simvastatin group.

[Effects of the stilbene extracts from Cajanus cajan L. on ovariectomy-induced bone loss in rats].

The Cajanus cajan L. is a natural plant, which contains lots of potential active components. The effects of the stilbene extracts from Cajanus cajan L.

[Effects of the extracts of Cajanus cajan L. on cell functions in human osteoblast-like TE85 cells and the derivation of osteoclast-like cells].

The cajanine (longistylin A-2-carboxylic acid) is isolated and identified from extracts of Cajanus cajan L. (ECC) , which structure is similar to diethylstilbestrol. The regulation properties of the cajanine and other four extracts of Cajanus cajan L.

[Comparative study of barium enema, computed tomography and magnetic resonance imaging in preoperative diagnosis of colorectal carcinoma].

Objective: To compare the diagnostic value of barium enema (BE), computed tomography (CT) and magnetic resonance imaging(MRI) in primary colorectal carcinoma.

Methods: A total of 64 patients with suspected colorectal carcinoma received BE (n=39), spiral CT (n=31) and MRI (n=42). The detective results were compared with the surgical results.

Siraitic acid F, a new nor-cucurbitacin with novel skeleton, from the roots of Siraitia grosvenorii.

A new cucurbitane triterpene, siraitic acid F (1), has been isolated from the roots of Siraitia grosvenorii (Swingle) C. Jeffrey, and its structure has been elucidated as 29-nor-4,24-diene-3,11-dioxo-19-hydroxy-6,19-cyclocucurbitane-26-oic acid on the basis of spectroscopic evidences, including a series of 2D NMR analyses.

[Studies on the new triterpenoid saponin of the aerial part of Cimicifuga foetida].

Objective: To find new active constituents from the aerial part of Cimicifuga foetida.

Method: Various column chromatographic techniques were used for the isolation and purification of the principles. The structures were elucidated on the basis of spectral data and chemical evidences.

[Studies on new trierpenoid constituents from the Rhizoma of Cimicifuga foetida].

Objective: To find new active constituents from Rhizome of Cimicifuga foetida.

Method: Various column chromatographic techniques were employed for isolation and purification. The structures were elucidated on the basis of spectral and chemical evidences.

Two new cyclolanostanol glycosides from the aerial parts of Cimicifuga foetida.

Two new cyclolanostanol glycosides, cimifoetiside IV (1) and cimifoetiside V (2) and two known compounds have been isolated from the aerial part of Cimicifuga foetida L. On the basis of spectral and chemical evidences, the structures of 1 and 2 were elucidated to be 25-O-acetylcimigenol-3-O-beta-D-glucopyranosyl-(1" --> 2')-beta-D-xylopyranoside (1) and cimigenol-3-O-beta-D-glucopyranosyl-(1"' --> 2")-beta-D-glucopyranosyl-(1" --> 2')-beta-D-xylopyranoside (2). The known compounds were identified as 25-O-acetylcimigenol-3-O-beta-D-glucopyranosyl-(1 --> 3)-beta-D-xylopyranoside (3) and 23-O-acetylshengmanol-3-O-beta-D-glucopyranosyl-(1 --> 3)-beta-D-xylopyranoside (4).

[Studies on the chemical constituents from the aerial parts of Cimicifuga dahurica].

Aim: To seek for new bioactive constituents from the aerial parts of Cimicifuga dahurica.

Methods: Various column chromatographic techniques were employed for the isolation and purification of the ingredients. The structures were elucidated on the basis of 1H, 13CNMR, 1H-1H COSY, HMQC, NOESY and HMBC spectra and chemical reactions.

[Studies on the phenolic acid constituents from Chinese medicine "sheng-ma", rhizome of Cimicifuga foetida L].

Aim: To look for new active constituents from Chinese medicine "Sheng-ma", rhizome of Cimicifuga foetida L.

Methods: The compounds were separated and purified by chromatography on silica gel and Sephadex LH-20. Their structures were determined by spectral analysis and chemical reaction.

[Studies on the chemical constituents of the aerial part of Cimicifuga foetida L].

Aim: To look for new active constituents from the aerial part of Cimicifuga foetida L.

Methods: Various column chromatographic techniques were used for the isolation and purification of the principles. The structures were elucidated on the basis of spectral data and chemical evidences.

[Studies on the triterpenoid constituents from the aerial part of Cimicifuga foetida L].

Aim: To look for new active constituents from the aerial part of Cimicifuga foetida L.

Methods: Various column chromatographic techniques were used for the isolation and purification of the ingredients. The structure were elucidated on the basis of spectral evidences and chemical reaction.