Publications by authors named "Di-Yuan Yang"

Purpose: Plastic bronchitis (PB), a rare complication of respiratory infection characterized by the formation of casts in the tracheobronchial tree, can lead to airway obstruction and severe condition. Adenovirus is one of the common pathogens of PB caused by infection. This study aimed to evaluate the clinical features and risk factors for PB in children with severe adenovirus pneumonia.

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Background: Human adenovirus (HAdV) is one of the most common viruses causing respiratory infections among young children. Most adenovirus infections are mild and self-limited; however, these infections may occasionally cause severe pneumonia and even death. The mortality risk factors for severe adenovirus pneumonia are not completely clear.

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Article Synopsis
  • Adenovirus pneumonia can lead to serious health issues in children, and bronchoalveolar lavage (BAL) is used as a treatment to help those with severe symptoms.
  • The study analyzed 134 children with adenovirus pneumonia, dividing them into mild and severe cases and further categorizing them based on whether they received BAL early or late (within 1-9 days vs. 10-14 days of illness).
  • Results showed that early BAL reduced hospital duration and fever in mild cases, but in severe cases, early BAL did not show significant benefits and was associated with more complications and the need for mechanical ventilation.
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Background: Some antibodies and autoreactive antibodies are associated with the severity of infectious diseases. The roles of humoral responses to lung inflammation in children with human adenovirus (HAdVs) pneumonia remain unknown.

Patients And Methods: A retrospective study was done to compare plasma immunoglobulin E (IgE) levels between HAdVs pneumonia patients and healthy children by searching the electronic medical record system of Guangzhou Women and Children's Medical Center.

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Objective: The efficacy of pulmonary surfactant (PS) replacement therapy for meconium aspiration syndrome (MAS) remains controversial. This study aimed to evaluate the efficacy of PS therapy in neonates with MAS by a meta-analysis.

Methods: Randomized controlled trials (RCTs) on the treatment of MAS with PS were searched electronically in medical debases including PubMed, Science Citation Index, The Cochrane Central Register of Controlled Trials, Ovid, EBSCOhost, BIOSIS previews, Chinese BioMedical Literature Database, Wanfang Database and VIP Chinese Sci-Tech Periodical Database.

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