Publications by authors named "Di-En Yan"
Juxtaglomerular cell tumor (JCT) is an endocrine tumor marked by elevated renin levels and high blood pressure. This case report presents the clinical findings of a 47-year-old woman with a history of recurrent hypokalemia, headaches, hypertension, and increased plasma renin activity (PRA). Dynamic enhanced magnetic resonance imaging (MRI) revealed a small nodule on the upper part of the right kidney.
View Article and Find Full Text PDFBackground: Iodine is an essential element for the biosynthesis of thyroid-stimulating hormone (TSH). Both excessive and deficient iodine are major risk factors for thyroid diseases, including thyroid dysfunction, thyroid nodules, and thyroid autoimmunity (TAI). This study aimed to elucidate the relationship between iodine status and the prevalence of thyroid diseases through a national cross-sectional epidemiological survey in Jiangxi province (China).
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- The study aimed to analyze how different durations of high glucose infusion affect insulin secretion and content in mouse β cells after an intravenous glucose load.
- Mice were divided into two groups receiving high glucose (25% dextrose) for either 2 or 4 hours, with control groups receiving saline, and several tests measured insulin response and content.
- Key findings revealed that the 4-hour high glucose group had significantly higher blood sugar levels and reduced first-phase insulin responses and insulin content in β cells compared to the 2-hour group, indicating a negative impact of prolonged glucose exposure on insulin secretion.