Publications by authors named "Di-Di Wen"
Article Synopsis
- The study focuses on developing a radiomic signature from MRI scans to predict disease-free survival (DFS) in patients with locally advanced cervical cancer who received chemoradiotherapy.
- It involved analyzing MRI data from 263 patients and used statistical methods like LASSO and Cox regression to create a signature highlighting four key features associated with poorer DFS.
- Results showed that this radiomic signature performed better in predicting DFS compared to traditional clinical models, suggesting its potential as a valuable non-invasive prognostic tool for high-risk patients.
Endothelial progenitor cells (EPCs) have an essential role in counteracting risk factor‑induced endothelial injury and protecting against the development of vascular injury, such as myocardial infarction. Magnetic resonance imaging (MRI) was reported to be effective in tracking transplanted stem cells following cell‑labeling with superparamagnetic iron oxide (SPIO) nanoparticles. SPIO has previously been used to label and track EPCs; however, the safest concentration of SPIO for labeling EPCs on a cellular level has remained to be elucidated.
View Article and Find Full Text PDFOne of the most fascinating findings in retrovirology is the construction of viral vectors based on foamy viruses (FVs) for gene therapy. The envelope glycoprotein (Env), one of the structural proteins of FV, is an important antigen in the immunoassays, as it is highly specific. To compare the characteristics of all 15 available FV Envs, the phylogenesis, hydrophobicity, modifications, and conserved motifs were analyzed based on the Env sequences.
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