Publications by authors named "Di-Cody Kang"
Article Synopsis
- OxlT is an oxalate transporter from Oxalobacter formigenes, part of the Major Facilitator Superfamily (MFS), which plays a crucial role in moving various solutes across membranes.
- Experimental studies have characterized OxlT as an electrogenic exchanger for oxalate and formate, revealing its three-dimensional structure and its biochemical properties.
- The review compares OxlT’s structure and function with other significant MFS transporters like LacY and GlpT, highlighting its importance in solute transport physiology and potential drug development.
OxlT, the oxalate transporter of Oxalobacter formigenes, was studied to determine its oligomeric state in solution and in the membrane. Three independent approaches were used. First, we used triple-detector (SEC-LS) size exclusion chromatography to analyze purified OxlT in detergent/lipid micelles.
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