Risk of significant gynaecological pathology in women with glandular neoplasia on cervical cytology.

Objective: To review the risk of pre-invasive and invasive gynaecological pathology in women referred with cervical cytology reporting ?glandular neoplasia.

Methods: Review of the case notes of all women referred with cervical cytology reported as ?glandular neoplasia between January 1999 and December 2008 at two UK hospitals: Portsmouth Hospitals NHS Trust and Queen Mary's Hospital Sidcup. The category of 'borderline nuclear change in endocervical cells', result code 8 according to the national health service cancer screening programme (NHSCSP), was excluded from the study.

Examination of cytological smears and clot sections prepared from pleural fluids: a comparative study.

Between January 1989 and May 1990, the Department of Cytology of Llandough Hospital examined 784 pleural fluid cytological preparations, 99 of which were also examined as paraffin wax sections of clots that had formed. To assess whether this practice yields worthwhile information, we reviewed the cytology and clot sections of 99 patients with pleural effusions and correlated the results with subsequent histology and review of clinical case notes. The specificities of each method separately and when combined was high: 92% clot section, 85% smear cytology and 85% combined.

Constrictive pericarditis in B cell chronic lymphatic leukaemia.

We report a case of B-cell chronic lymphatic leukaemia (B-CLL) complicated by constrictive pericarditis. The pericardial involvement was confirmed histologically to be leukaemic in nature. We draw attention to this complication which is amenable to surgical correction.

An immunohistological study of granulomatous prostatitis.

Granulomatous prostatitis may result from tuberculosis and fungal infection and has been described following prostatic surgery. In most cases, however, the aetiology is unknown, although it may be due to a reaction to extravasated or altered prostatic secretions. We have investigated cells (macrophages, lymphocytes), serum proteins (fibrinogen, alpha 1-antitrypsin) and prostatic epithelial products (prostatic-specific antigen and prostatic acid phosphatase) in diffuse granulomatous prostatitis (3 cases), focal periacinar prostatic granulomas (9) and focal prostatic infarcts (5), using an immunohistological technique.

Comparison of two preparatory techniques for urine cytology.

Two methods of preparation of urine for cytology were compared retrospectively. In method 1 cells in the urine were fixed after the preparation of the smear; in method 2 the cells were fixed before smear preparation. Urine cytology reports were correlated with subsequent histological analysis.