Background: Gingivitis is a dysbiotic condition characterized by persistent inflammation caused by a disease-associated multispecies bacterial population that has established itself in the subgingival region.
Aim: The objectives of this study are to analyze the anti-inflammatory activity of sappan wood extract cream (SWC) in induced-periodontitis rats model.
Methods: In this study, rats were infected with the gingiva with as an inducer for gingivitis rats model for 14 days.